ASSESSMENT VENOUS THROMBOEMBOLISM RISK IN HOSPITALIZED MEDICAL PATIENTS WITH CARDIOVASCULAR DISEASE BY PADUA SCORE

Trịnh Ngọc Thạnh1,2, Hoàng Văn Sỹ1,2,
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Cho Ray Hospital

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Abstract

Background: Venous thromboembolism (VTE) is a common disease that causes a high morbidity and mortality rate, especially in hospitalized patients with many underlying medical conditions. Therefore, assessing the risk of  VTE and using appropriate prophylaxis play an important role in clinical practice. Objective: Assessment of venous thromboembolism risk in hospitalized medical patients with cardiovascular disease by Padua score. Methods: Retrospective study, surveying of patients in Cardiology Department at Cho Ray Hospital from October 2021 to May 2022. Results: From October 2021 to May 2022, 404 patients were selected for the study. In which, there are 206 female patients (accounting for 51%). The mean age was 58.2 ± 18.5 years. There are 56.7% patients at high risk of VTE (Padua ≥ 4 points). The factors that appear commonly in the Padua score are: Immobility (58.9%), heart or respiratory failure (51.2%), acute infection (47%), age ≥ 70 years (30%), acute myocardial infarction (10.6%). The group of patients with heart failure with reduced ejection fraction had a higher risk of VTE according to the Padua score than the group with mildly reduced and preserved ejection fraction (p = 0.003). In the group of patients with high risk of VTE, there was 76.9% high risk of bleeding (IMPROVE > 7 points) or contraindications to anticoagulation. Conclusion: In hospitalized patients with cardiovascular disease, a large proportion have a high risk of VTE according to the Padua score. However, the majority of patients with high bleeding risk or contraindications to anticoagulation make it difficult to prevent VTE in hospital.

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References

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