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Date Published: 19/02/2023
Abstract Views: 183
Views PDF: 218
DOI: https://doi.org/10.51298/vmj.v522i2.4352
Issue
Vol. 522 No. 2 (2023)
Section
Các bài báo
How to Cite
Đặng , X. H., Mai , Q. T., & Nguyễn, T. T. T. . (2023). EVALUATE THE EFFECTIVENESS OF SPIRONOLACTONE IN THE TREATMENT OF SERIOUS CENTRAL RELATIONSHIP. Vietnam Medical Journal, 522(2). https://doi.org/10.51298/vmj.v522i2.4352

EVALUATE THE EFFECTIVENESS OF SPIRONOLACTONE IN THE TREATMENT OF SERIOUS CENTRAL RELATIONSHIP

Xuân Hoa Đặng 1,, Quốc Tùng Mai 1,2, Thị Thu Trang Nguyễn3
1 Hanoi medical university
2 National Geriatric Hospital
3 ThaiBinh University of Medicine and Pharmacy

Main Article Content

Abstract

Objective: Evaluate the effectiveness of spironolactone in the treatment of central serous chorioretinopathy. Method: Prospective descriptive study on 44 eyes of 41 patients with serous central chorioretinopathy who were prescribed oral spironolactone at a dose of 50 mg/day for 12 weeks. from August 2021 to August 2022 at the Department of Ophthalmology - National Geriatric Hospital. Results: 44 diseased eyes of 41 patients diagnosed with serous central chorioretinopathy after 12 weeks of treatment all had a significant change in visual acuity compared to baseline, 47.7% had good vision improvement, 50% had improvement. average and only 1 eye, accounting for 2.3%, had no improvement in visual acuity. Anatomically, there was a marked change, after 12 weeks, the height of the subretinal fluid decreased from 242.82± 128.02 µm to 26.45± 48.57 µm, The number of eyes with subretinal fluid was reduced. complete resolution is 70.5%. The central retinal thickness decreased from 442,11 ± 129,69 µm initially to 257,18 ± 43,70 µm after 12 weeks of treatment. The area of ​​the serous effusion decreased from 12.30 ± 6.92 mm2 initially to 1.25 ± 2.15 mm2 after 12 weeks and there were no cases of side effects. Conclusion: Spironolactone at a dose of 50 mg/day orally had a significant improvement in function and anatomy in the treatment of central serous chorioretinopathy. Spironolactone is a safe and effective choice for patients with central serous chorioretinopathy.

Article Details

Keywords

Central serous chorioretinopathy, spironolactone

References

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