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EVALUATING THE RESULTS OF BREAST CANCER PATIENTS TREATED WITH BREAST CONSERVING SURGERY AND SENTINEL LYMPH NODE BIOPSY AT K HOSPITAL
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Abstract
Purpose: To evaluate the results of breast conserving surgery (BCS) and sentinel lympho node biopsy (SLNB) on breast cancer patients at K hospital from 2012-2014. Patients and Methods: This retrospective descriptive study was conducted on 84 breast cancer patients stages cT1N0M0-cT2N0M0, tumor size less than 3cm and underwent BCS and SLNB by the use of methylene blue from 2012 to 2014 at K hospital. Axillary lymph node dissections (ALNDs) were only done with positive SLNB or not identified. Results: The average age was 48,1 years, mean tumor size was 1,4cm. The identification rate of sentinel lymphnodes (SNs) was 100% using methylene blue with the SLN positive was 5,9%. The average follow-up period was 98,1 months (range 16:120 months). The local recurrence in ipsilateral breast and local-regional node recurrence was 4,7% and 2,38%, respectively. The distant recurrence rate was 10,7% and death rate was 9,5%. 8 years - overall survival (OS) and disease free survival (DFS) was 90,5% and 83,3% respectively. Conclusion: Breast conserving surgery and sentinel lymph node biopsy is safe, effective and necessary operation for early breast cancer treatment.
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Keywords
Early breast cancer; Breast conserving surgery; Sentinel lymph node biopsy
References
2. Veronesi U, Viale G, Paganelli G, et al. Sentinel lymph node biopsy in breast cancer: ten-year results of a randomized controlled study. Ann Surg. 2010;251(4):595-600. doi:10.1097/ SLA. 0b013e3181c0e92a
3. Hồng Quang L, Văn Đức N. Kết quả phẫu thuật bảo tồn ung thư vú áp dụng các kỹ thuật tạo hình với khối u tại vị trí ít nhu mô tuyến vú. Tạp Chí Học Việt Nam. 2022;51(2):65.
4. Hồng Quang L, Anh Dũng H. Kết quả phẫu thuật bảo tồn ung thư vú có sử dụng kỹ thuật tạo hình round block cho khối u nửa trên tuyến vú. Tạp Chí Học Việt Nam. 511(2(2)):225.
5. Takahashi S, Murakami Y, Imano N, et al. Long-term results after 12-year follow-up of patients treated with whole-breast and boost irradiation after breast-conserving surgery. Jpn J Radiol. 2016;34(9):595-604. doi:10.1007/s11604-016-0562-2
6. Li W, Zheng Y, Wu H, Li X. Breast-conserving therapy versus mastectomy for breast cancer: a ten-year follow-up single-center real-world study. Gland Surg. 2022;11(7):1148-1165. doi:10.21037/ gs-22-142
7. Blichert-Toft M, Nielsen M, Düring M, et al. Long-term results of breast conserving surgery vs. mastectomy for early stage invasive breast cancer: 20-year follow-up of the Danish randomized DBCG-82TM protocol. Acta Oncol Stockh Swed. 2008;47(4):672-681. doi:10.1080/ 02841860801971439
8. Tứ Quý T. Đánh giá bước đầu tình trạng di căn hạch nách trong ung thư vú. Học TpHCM. 2008;12(4):256.
9. Botteri E, Bagnardi V, Rotmensz N, et al. Analysis of local and regional recurrences in breast cancer after conservative surgery. Ann Oncol Off J Eur Soc Med Oncol. 2010;21(4):723-728. doi:10.1093/annonc/mdp386
10. Miles RC, Gullerud RE, Lohse CM, Jakub JW, Degnim AC, Boughey JC. Local recurrence after breast-conserving surgery: multivariable analysis of risk factors and the impact of young age. Ann Surg Oncol. 2012;19(4):1153-1159. doi:10.1245/ s10434-011-2084-6
11. Elsayed M, Alhussini M, Basha A, Awad AT. Analysis of loco-regional and distant recurrences in breast cancer after conservative surgery. World J Surg Oncol. 2016;14:144. doi:10.1186/s12957-016-0881-x