VALUE OF ESTIMATED PLASMA VOLUME STATUS (EPVS) IN ASSESSMENT OF VOLUME STATUS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

Đăng Quân Nguyễn1, Ngọc Sơn Đỗ2,3,4, Anh Tuấn Nguyễn1,3, Tuấn Anh Bùi 3
1 Hanoi medical university
2 Hanoi medicl university
3 Bach Mai hospital
4 VNU - School of Medicine and Pharmacy

Main Article Content

Abstract

Objectives: To evaluate the estimated plasma volume index (ePVS) in the assessment of volume status in patients with acute myocardial infarction. Subjects and methods: 85 patients aged ≥ 18 years old, regardless of sex, with the diagnosis of acute myocardial infarction or heart failure after myocardial infarction, without complication of cardiogenic shock were treated at A9 Emergency Center, Bach Mai Hospital from January 2021 to August 2022. This was an analytical cross-sectional descriptive study evaluating the relationship between ePVS and patient's volume status. Results: Patients with dyspnea based on NYHA III, NYHA IV had mean ePVS values ​​of 4.7 ± 2.2 (g/dL) and 4.9 ± 1.7 (g/dL), respectively, higher than those of NYHA I, NYHA II (p <0.01). The ePVS index in patients with fluid overload and heart failure with reduced ejection fraction (EF < 40%) was 5.5 ± 4.4 (g/dL) higher than that in the preserved ejection fraction (EF>50%) which was 4.3 ± 1.9 (g/dL) (p < 0.01). The ePVS index was strongly correlated with other volume status parameters such as inferior vena cava diameter (IVC), central venous pressure (CVP) with the correlation coefficient r = 0.77, (p < 0.05) and r = 0.63 (p < 0.05). In patients with volume overload, high IVC or high CVP values had higher mean ePVS values ​​of 4.6 ± 2.5 (g/dL) and 4.6 ± 1.2 (g/dL), respectively on admission. Conclusion: Estimated plasma volume status (ePVS) is a simple, easy-to-use, low-cost indicator for the continuous monitoring and assessment of volume status in patients with acute myocardial infarction.

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References

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