ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ VÚ BỘ BA ÂM TÍNH TÁI PHÁT DI CĂN

Abstract

Objectives: Clinical and subclinical characteristics of patients with recurrent and metastatic in triple negative breast cancer at K hospital. Patients and methods: Retrospective descriptive study of 95 patients were diagnosed recurrent or metastatic in triple negative breast cancer at K hospital. Results: 95 patients enrolled in the study. The mean age at the time of recurrent or metastatic was 47.3 years. The most common time for patients to relapse was the first 2 years after radical treatment, accounting for 64.7%. Mean disease-free survival was 18.9 months. The patients who relapsed at the time after 3 years only accounted for 17.1%. The most common sites of metastasis were lung, liver and bone accounting for 48.4%, 34.7% and 23.1%, respectively. 68.4% of patients had visceral metastases, in which 17.9% of patients had metastases from 2 organs or more. At the time of diagnosis, 52.6% of patients had elevated CA15-3 levels. Conclusion: Triple negative breast cancer has a very high rate of metastatic recurrence in the first years after radical treatment, especially in the first 3 years. Patients have a high rate of visceral metastasis while the rate of bone metastasis is lower than that of the others breast cancer subtypes.