EARLY RESULT OF MINOR ANATOMICAL LIVER RESECTION FOR HEPATOCELLULAR CARCINOMA AT VIET DUC UNIVERSITY HOSPITAL

Việt Khải Ninh1,, Quang Tiến Dương2
1 Viet Duc hospital
2 Bac Giang general hospital

Main Article Content

Abstract

Objectives: To evaluate early results of minor liver resection and effect factors. Patients and method: Retrosp ective cross-sectional study of 129 patients with hepatocellular carcinoma were performed minor liver resection in Viet Duc hospital from 1/2015 to 1/2020. Results: The average age 52.8 ± 12.4 years old, the male/female ratio: 4/1, the patients with hepatitis B: 26.35%. Patients admitted to the hospital because of abdominal pain were the most common, accounting for 46.5%. Average  AFP: 736.97 ± 1612.7 (0.06 - 7725) ng/ml. There are 33% of patients with AFP value > 200 ng/ml. The average time operation: 225.1 ± 70.6 minutes. The overall rate of complications after surgery: 47.2%; pleural effusion had a rate of 39.5% which was the most common complication in the study. Residual outbreaks have the rate of 13.18%, the rate of postoperative bleeding is 1.6%, the rate of postoperative liver failure is 0.78%. There was 1 case of postoperative death (within 1 month after surgery). The mean hospital stay: 10.4  days. Surgery time over 240 minutes, age over 60 are factors affecting postoperative complications. Conclusion:   Minor liver resection for hepatocellular carcinom is safe, most of the complications are mild and mortality rate is low.

Article Details

References

1. Bruix J, Sherman M. Management of hepatocellular carcinoma: an update. Hepatology. Mar 2011;53(3):1020-2.
2. Đỗ Bá Hùng, Võ Văn Hùng, Nguyễn Cao Cương, et al. Kết quả sớm của phẫu thuật cắt gan theo cuống bao glisson. Tạp chí y học thành phố Hồ Chí Minh. 2018;22(2):205-210.
3. Lee CW, Chan KM, Lee CF, et al. Hepatic resection for hepatocellular carcinoma with lymph node metastasis: clinicopathological analysis and survival outcome. Asian journal of surgery / Asian Surgical Association. Apr 2011;34(2):53-62.
4. Ercolani G, Grazi GL, Ravaioli M, et al. The role of lymphadenectomy for liver tumors: further considerations on the appropriateness of treatment strategy. Ann Surg. Feb 2004; 239(2):202-9.
5. Chau GY, Lui WY, Tsay SH, et al. Prognostic significance of surgical margin in hepatocellular carcinoma resection: an analysis of 165 Childs' A patients. Journal of surgical oncology. 1997; 66(2):122-126.
6. Balzan S, Belghiti J, Farges O, et al. The "50-50 criteria" on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy. Ann Surg. Dec 2005;242(6):824-8, discussion 828-9.
7. Kamiyama T, Nakanishi K, Yokoo H, et al. Perioperative management of hepatic resection toward zero mortality and morbidity: analysis of 793 consecutive cases in a single institution. Journal of the American College of Surgeons. Oct 2010;211(4):443-9.
8. Capussotti L, Muratore A, Amisano M, Polastri R, Bouzari H, Massucco P. Liver resection for hepatocellular carcinoma on cirrhosis: analysis of mortality, morbidity and survival--a European single center experience. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. Nov 2005;31(9):986-93.