HIỆU QUẢ ĐIỀU TRỊ UNG THƯ THỰC QUẢN 1/3 TRÊN ÁP DỤNG CONE-BEAM COMPUTED TOMOGRAPHY (CBCT) TRONG XẠ TRỊ ĐIỀU BIẾN LIỀU TẠI BỆNH VIỆN K

Abstract

Background and aims: The purpose of this study was to evaluate upper oesophageal cancer treatment effect based on anatomical variations using deformable image registration methods of ConeBeam CT (CBCT). Patients and methods: In 40 patients with upper esophageal cancer, four “clipbox” (C) volumes were defined: C-planning target volume (PTV), C-carina, C-vertebrae, C-thorax. The set-up corrections (translational and rotational) for C-PTV were compared to the ones using C-carina, C-vertebrae and C-thorax. Results: From 40 patients, 1120 ConeBeam CT-scans were registered. The highest concordance in set-up corrections between C-PTV and C-carina in the superior/inferior direction was found at 60,7%; in the right/left and anterior/posterior directions was at 88,7% and 82% respectively. C-vertebrae in ConeBeam CT was found with the highest setup errors. Conclusion: Anatomical changes can result in the correction of patient positioning errors which are difficult to be detected during clinical examination. To achieve the best radiotherapy treatment result for upper-oesophageal tumours, it is vital to calculate accurate planning target volume.