TECHNICAL CHARACTERISTICS AND RESULTS OF PORTAL VEIN RECONSTRUCTION IN LIVING DONOR LIVER TRANSPLANTATION USING RIGHT LOBE GRAFT

Văn Thành Lê1, Văn Quang Vũ 1, Trung Hiếu Lê1,
1 108 Military Central Hospital

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Abstract

Objective: To evaluate the technical characteristics and results of portal vein reconstruction in right lobe graft living donor liver transplantation. Subject and method: The prospective study was performed on 52 cases of living donor liver transplantation using right lobe graft at 108 Military Central Hospital from January 2019 to December 2020. Results: 100% of the portal vein anatomical anastomosis were performed in an end-to-end fashion using continuous sutures. The thrombectomy was performed in 4 cases of PVT grade I and II. Two cases were performed simultaneous splenectomy during LDLT, and five cases underwent portosystemic collaterals ligation. There were 5 cases of portal vein complications (9,6%). Portal vein stenosis was diagnosed and treated successfully by stent placement in 2 cases (3,8%). The remaining cases were due to recurrent thrombosis and compression by hematoma (5,8%), which were successfully managed conservatively. Conclusion: It is necessary to assess the anatomical variation and non-tumoral thrombosis of the portal vein before transplantation to select the most most appropriate reconstruction method. The stent placement is a safe and effective treatment for portal vein stenosis. 

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References

1. Guler N, Dayangac M,Yaprak O (2013). “Anatomical variations of donor portal vein in right lobe living donor liver transplantation: the safe use of variant portal veins”. Transplant International, 26: 1191–1197.
2. Hwang S, Lee SG,Ahn CS (2009). “Technique and outcome of autologous portal Y-graft interposition for anomalous right portal veins in living donor liver transplantation”. Liver Transplantation, 15: 427-434.
3. Yaprak O, Guler N, Balci NC (2012). “A new technique for the reconstruction of complex portal vein anomalies in right lobe living liver donors”. Hepatobiliary Pancreat Dis Int, 11: 438-441.
4. Miura K, Sugawara Y, Uchida K (2018). “Adult living donor liver transplantation for patients with portal vein thrombosis: a single-center experience”. Transplantation Direct, 4(5): e341.
5. Yoshizumi T, Mori M (2020). “Portal flow modulation in living donor liver transplantation: review with a focus on splenectomy”. Surg Today, 50(1): 21-29.
6. Reddy MS, Rela M (2017). “Portosystemic collaterals in living donor liver transplantation: What is all the fuss about?”. Liver Transpl, 23: 537–544.
7. Sare A, Chandra V,Shanmugasundaram S (2021). “Safety and efficacy of endovascular treatment of portal vein stenosis in liver transplant recipients: A systematic review”. Vasc Endovascular Surg, 55(5): 452-460.
8. Kim KS, Kim JM,Lee SK (2019). “Stent insertion and balloon angioplasty for portal vein stenosis after liver transplantation: long-term follow-up results”. Diagn Interv Radiol, 25(3): 231-237.
9. Jang ỴJ, Kim KW, Jeong WK (2010). “Influence of preoperative portal hypertension and graft size on portal blood flow velocity in recipient after living donor liver transplantation with right-lobe graft”. AJR, 194: 165-170.
10. Shibasaki S, Taniguchi M,Shimamura T (2010). “Risk factors for portal vein complications in pediatric living donor liver transplantation”. Clin Transplant, 24: 550–556.