BÁO CÁO CA BỆNH HỘI CHỨNG THỰC BÀO TẾ BÀO MÁU SAU NHIỄM CÚM A (H1N1) ĐIỀU TRỊ TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI TRUNG ƯƠNG

Abstract

Background: Influenza A (H1N1) usually causes mild clinical symptoms and can be self-limiting, in some cases, it may develop abnormally and cause hemophagocytic lymphohistiosis syndrome (HLH). It is a serious, life-threatening medical condition. Materials and methods: Description of clinical and subclinical symptoms and results of treatment in a 13-year-old male child infected with influenza A (H1N1) treated at the National Hospital for Tropical Diseases. Results: A 13-year-old boy had onset of symptoms with cough, fever, yellow skin and eyes, anemia, hepatosplenomegaly, no difficulty breathing, no rales in the lungs. PCR test for influenza A (H1N1) was positive, red blood cells decreased (2.82T/l), white blood cells decreased (2.6T/l), platelets decreased (37G/l), ferritin increased (950ng/ml), myelogram showed blood phagocytosis. The patient was diagnosed with HLH - influenza A (H1N1) infection according to HLH-2004, chemotherapy treatment according to HLH-2004 regimen, anti-influenza antiviral and transfusion of red blood cells and fresh plasma. Treatment results, children responded well to treatment, gradually stabilized in clinical and subclinical conditions, and the children were discharged from the hospital. Conclusion: Attention should be paid to secondary HLH in patients with an unusual course of infection.