KHẢO SÁT TÌNH HÌNH ĐỀ KHÁNG KHÁNG SINH CỦA CÁC CHỦNG VI KHUẨN GÂY BỆNH THƯỜNG GẶP TẠI KHOA HỒI SỨC TÍCH CỰC CỦA BỆNH VIỆN NGUYỄN TRI PHƯƠNG GIAI ĐOẠN 2019-2021

Abstract

Objective: Describe the prevalence and the susceptibility patterns of common bacterial isolated from patients at the Intensive care unit in Nguyen Tri Phuong Hospital to several antimicrobials from 2019 to 2021. Materials and methods: Data on antimicrobial susceptibility were collected retrospectively from the Hospital Laboratory between January 2019 and December 2021. Results: Over the years 2019 - 2021, there were 6189 samples cultured at the Intensive care unit (ICU). After three years, there were no vancomycin-resistant Staphylococcus spp. strains with vancomycin MIC > 2 µg/mL and linezolid according to CLSI 2021. The rate of MRSA in the ICU is high. In which, the rate of MRSA with vancomycin MIC in the range of 1-2 µg/mL accounted for 15.8%. The susceptibility of E. coli was still sensitive over 50% to a few antibiotics and it was highly sensitive to carbapenems and aminoglycosides. K. pneumoniae had a susceptibility rate of less than 50% to all tested antibiotics. Acinetobacter spp. has a sensitivity of less than 20% to most of the tested antibiotics, only complete sensitivity to colistin, doxycycline (52.6%) and co-trimexazole (31.4%). P. aeruginosa has a sensitivity rate of less than 50% to quinolones, meropenem and 2.6% to co-trimexazole. Burkholderia spp. had a sensitivity of more than 50% to most antibiotics. Conclusion: The antibiotic susceptibility pattern in the Intensive care unit varied among the six commonly bacteria strains, but overall, the sensitivity tended to decrease. In which, Acinetobacter spp. has the lowest antibiotic sensitivity rate.