TEST RESULTS OF VIRUS NEGATIVE TEST AND RELATED FACTORS AT THAI NGUYEN NO. 1 COVID-19 HOSPITAL

Đắc Trung Phạm 1,, Hà Hoàng1, Khánh Linh Tống 1, Thị Thùy Linh Lê1, Quý Trọng Quang Nguyễn1
1 Thai Nguyen University Of Medicine And Pharmacy

Main Article Content

Abstract

Objectives: Determine the negative results and describe some factors related to the negative results in mild and moderate COVID-19 patients. Subjects: Mild and moderate COVID-19 patients were treated at Thai Nguyen No. 1 COVID-19 Hospital from January 1, 2022 to April 13, 2022. Methods: Cross-sectional descriptive, retrospective. Sample size: 2000 patients. Virus identification by RT-PCR assay. Early negative time was calculated from 7 days from hospital admission to negative result for SARS-CoV-2, >7 days was defined as late negative time. Data processing by medical statistics. Results: The average time of sonication was 8.04±3.167 days, early (45.55%), late (54.45%). The factors of gender, BMI, time of diagnosis were not related to the time of sonication. There is a relationship between early sonication time and factors such as age (p<0.01), pregnancy (p<0.01), vaccination (p<0.01), and taste and smell disorders (<0.01). 0.01), lymphopenia (<0.01), thrombocytopenia (<0.01), increased CRP (<0.01), prolonged D-dimer (<0.01), X-ray lung (<0.01). Conclusion: Factors <15 years old, no pregnancy, no taste-smell disorder, lymphocytes >1.5G/l, CRP <5 mg/l, platelets >150 G/l, D-dimer <0 ,5 mg/l and no abnormalities on chest x-ray help predict patients with high probability of early COVID-19 negative results

Article Details

References

1. Suleyman G, Fadel RA, Malette KM, et al. Clinical Characteristics and Morbidity Associated With Coronavirus Disease 2019 in a Series of Patients in Metropolitan Detroit. JAMA Netw Open. 2020;3(6):e2012270.
2. Hoàng Thị Lan Hương, Trần Thừa Nguyên, Nguyễn Trọng Nghĩa, Phạm Trung Hiếu, Hoàng Vĩnh Trung Hiếu, Phan Thị Phương, Ngô Thị Quỳnh Chi. “Đặc điểm lâm sàng và các dấu ấn sinh học tiên lượng của bệnh nhân COVID19’’ tại Bệnh viện Trung ương Huế. Tạp Chí Y Học Lâm Sàng Số 79/2022-Tr. 27-34
3. Pan Zhai, Yanbing Ding, Xia Wu, Junke Long, Yanjun Zhong, Yiming LiThe. Epidemiology, diagnosis and treatment of COVID-19. International Journal of Antimicrobial Agents Volume 55, Issue 5, May 2020, 105955.
4. Jamil, S., Mark, N., Carlos, G., Cruz, C. S. D., Gross, J. E., & Pasnick, S. Diagnosis and management of COVID-19 disease. American journal of respiratory and critical care medicine,(2020). 201(10), P19-P20.
5. Bernd Sebastian Kamps, Christian Hoffmann “COVID REFERENCE’’, 1th , pp 323-429.
6. Lopez-Leon, S., Wegman-Ostrosky, T., Perelman, C. et al. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Scientific Reports; 11(1):16144.
7. Faes C, Abrams S, Van Beckhoven D, Meyfroidt G, Vlieghe E, Hens N, Belgian Collaborative Group on COVID-19 Hospital Surveillance. Time between Symptom Onset, Hospitalisation and Recovery or Death: Statistical Analysis of Belgian COVID-19 Patients. International Journal of Environmental Research and Public Health. 2020; 17(20):7560.
8. Viktoriya London, Rodney McLaren Jr., Fouad Atallah, Catherine Cepeda, Sandra McCalla, Nelli Fisher, Janet L. Stein, Shoshana Haberman, Howard Minkoff “The Relationship between Status at Presentation and Outcomes among Pregnant Women with COVID-19”. American journal of perinatology (2020); 37(10): pp 991-994.