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Date Published: 27/04/2023
Abstract Views: 494
Views PDF: 239
DOI: https://doi.org/10.51298/vmj.v525i2.5164
Issue
Vol. 525 No. 2 (2023)
Section
Các bài báo
How to Cite
Đinh , D. T. A. ., Nguyễn, T. H. ., Lý , T. T. M., & Đinh , V. T. . (2023). CHARACTERISTICS OF SEPSIS AT HAIPHONG CHILDREN’S HOSPITAL IN 2014 - 2020. Vietnam Medical Journal, 525(2). https://doi.org/10.51298/vmj.v525i2.5164

CHARACTERISTICS OF SEPSIS AT HAIPHONG CHILDREN’S HOSPITAL IN 2014 - 2020

Dương Tùng Anh Đinh 1,2, Thị Huyền Nguyễn1, Thị Thương Mến Lý 1, Văn Thức Đinh 1,3,
1 Hai Phong University Of Medicine And Pharmacy
2 HAI PHONG CHILDREN'S HOSPITAL
3 Hai Phong University Of Medicine And Pharmacy hospital

Main Article Content

Abstract

Objectives: To characterize of pathogenic bacteria and results of treatment of sepsis at Hai Phong Children's Hospital in the years 2014-2020. Materials and methods: Children under 15 years old who were hospitalized at the Hai Phong Children's Hospital during 2014 – 2020, diagnosed with sepsis. The organisms were isolated using standard culture techniques, and then antibiogram was performed following the Kirby-Bauer disk diffusion susceptibility test protocol. Results: We enrolled 226 cases of sepsis in this study. The most common bacteria causing sepsis were: S. aureus (20.8%), S. epidermidis (14.2%), P. aeruginosa (11.9%) and K. pneumoniae (11.9%). S. aureus was susceptible to amikacin, gentamycin, vancomycin, meropenem, less sensitive to cephalosporins (2nd, 3rd generation) and already resistant to penicillin and oxacillin. P. aeruginosa was susceptible to amikacin, gentamycin, meropenem, vancomycin and ciprofloxacin; less sensitive to cephalosporins and oxacilin. The average LOS for sepsis in children was 9.39 ± 6.19 days. The rate of severe cases of referral or death due to sepsis was still high (27.4%). Conclusion: Our study demonstrated a wide range of Gram-positive and Gram-negative pathogens to be responsible for sepsis in Hai Phong children and a significant status of antibiotic resistance. The rate of treatment failure due to sepsis was still quite high, requiring further improvement in disease diagnosis and treatment.

Article Details

Keywords

sepsis, children, antibiotic resistance, S. aureus, P. aeruginosa

References

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