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Date Published: 27/04/2023
Abstract Views: 473
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DOI: https://doi.org/10.51298/vmj.v525i2.5207
Issue
Vol. 525 No. 2 (2023)
Section
Các bài báo
How to Cite
Nguyễn, B., Đỗ, H. T. ., & Trần, H. N. . (2023). CHERECTERICSTICS OF HISTOPATHOLOGICAL PATTERNS IN 300 PATIENTS WITH KIDNEY DISEASE PERFORMED RENAL BIOPSY AT THONG NHAT HOSPITAL. Vietnam Medical Journal, 525(2). https://doi.org/10.51298/vmj.v525i2.5207

CHERECTERICSTICS OF HISTOPATHOLOGICAL PATTERNS IN 300 PATIENTS WITH KIDNEY DISEASE PERFORMED RENAL BIOPSY AT THONG NHAT HOSPITAL

Bách Nguyễn1,, Hữu Tuyên Đỗ2, Hoài Nhân Trần2
1 Thong Nhat hospital
2 Pham Ngoc Thach University of Medicine

Main Article Content

Abstract

Objectives: To evaluate histopathological patterns in patients with kidney diseases performed renal biopsy at Thong Nhat Hospital. Methods: retrospective, descriptive cross-sectional study. Inclusion criteria: All patients who had renal biopsy at Thong Nhat Hosptital during the period of May 2012 – May 2022. Exclusion criteria: (1): The samples were not adequate for pathological analysis, (2): Second renal biopsy, (3): kidney transplant biopsy. Results: In primary glomerular disease, the percentage of minimal change disease (MCD), IgA nephropathy (IgAN), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN) and other lesions were 33.33%; 24.77%; 19.81%; 15.77%, and 6.32% respectively. The percentage of IgAN and Lupus nephritis (LN) in group <60 years old vs group ≥60 years old was 21.70% and 11.30% vs 7.10% and 1.4% respectively (p<0.05). The percentage of DN and tubular interstitial disease (TID) in group <60 years old vs group ≥60 years old was 3.50% and 2.60% vs 11.40% and 12.80% respectively (p<0.05). The percentage of MN was 17.70% vs 7.10% in 2017- 2022 vs 2012- 2017 (p<0.001). Conclusions: Through a survey of 300 kidney biosy samples at Thong Nhat Hospital, we found that a mong primary glomerular diseases, MCD is the most common, followed by IgA nephropathy and FSGS. IgA nephropathy and Lupus nephritis were more common in the young. Otherwise, DN and TID were more common in the elderly. MCD account for a low percentage of patients with kidney biosy indication as nephrotic syndrome. IgA nephropathy and FSGS were common in patients with kidney biosy indication as nephritic syndrome. IgA nephropathy is the most common in patients with kidney biosy indication as asymtomatic urinary abnormalities The incidence of MN has increased significantly in recent years.

Article Details

Keywords

Renal biopsy, kidney histopathology, minimal change disease, IgA nephropathy, membranous glomerulonephritis

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