MỐI LIÊN QUAN GIỮA CÁC BIẾN CỐ BẤT LỢI VÀ TRẦM CẢM Ở BỆNH NHÂN HIV ĐIỀU TRỊ NGOẠI TRÚ TẠI THÀNH PHỐ HỒ CHÍ MINH

Abstract

Introduction: HIV remains a significant global public health issue and causes many burdens that adversely affect both physical and mental health of HIV patients. Among factors contributing to depression, adverse events are important but little is known about these. Objectives: To determine the prevalence of depression, adverse events and the association between adverse events and depression in HIV outpatients in Ho Chi Minh City. Materials and methods: A cross-sectional study was conducted among 777 HIV outpatients at four outpatient clinics in district 3, district 6, district 8, and district 11 of Ho Chi Minh City. Patients were interviewed using a structured questionnaire. Depression was measured by the CES-D, which had been validated in Vietnam. Results: The prevalence of depression in HIV outpatients was 41.4%. The most common adverse events were having financial problems and occupation. About 37% of patients had 3 or more adverse events in the past 30 days. The number of adverse events was significantly associated with depression. Higher odds of having depression was found in patients 1-2 adverse events (OR=2.91; 95% CI: 1.72–4.94), 3–4 adverse events (OR=30.88, 95% CI: 17.21–55.41), 5 or more adverse events (OR=312.74, 95% CI: 112.46–869.75) compared to patients with no adverse event. Conclusion: The prevalence of depression in HIV outpatients is quite high, and there are many adverse events patients encounter. There is statistically significant association between the adverse events experienced by HIV outpatients and their symptoms of depression.