EVALUATION OF THE SCORE FOR NEONATAL ACUTE PHYSIOLOGY EXTENSION II TO PREDICT MORTALITY IN 552 NEWBORNS
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Abstract
Background: To assess the ability of the Score for Neonatal Acute Physiology version II (SNAP- II) to predict in-hospital mortality in newborns who were admitted in the Neonatal Intensive Care Unit (NCU). Methods: This study was conducted in Children’s Hospital 2, Vietnam between November 2016 to October 2018. A total of 552 newborns hospitalized in the Neonatal Intensive Care Unit were included. We collected all the physiology, and laboratory data for the first 24 hours needed to calculate SNAP-II at admission (SNAP-II(T0)) and 24 hours after admission SNAP-II(T1). The SNAP-II cut-off to predict in-hospital death was determined by comparing the area under the curve (AUC). Results: A total of 552 neonates admitted to NICU (357 newborns with birth weight > 1500g and 195 newborns with birth weight ≤ 1500g) were included meeting the criteria. The mortality rate was 23.6%. In a group of newborns with birth weight > 1500g, the SNAP-II(T0) and SNAP-II(T1) cut-offs were 13 and 15, the AUC of SNAP-II(T0) and SNAP-II(T1) were 0.839 and 0.879, p<0.001. In a group of newborns with birth weight ≤ 1500g, the SNAP-II(T0) and SNAP-II(T1) cut-offs were 20.5 and 6.0, the AUC of SNAP-II(T0) and SNAP-II(T1) were 0.656 and 0.733, p<0.001. Conclusion: According to our findings SNAP II is a useful tool in predicting mortality among neonates with birth weight > 1500g much better than neonates with birth weight ≤ 1500g. SNAP-II(T1) had a better predictive value compared to SNAP-II(T0).
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Keywords
NICU, SNAP-II, mortality
References
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