INVESTIGATION ON THE PROGNOSTIC VALUE OF THE LRINEC SCORE IN PATIENTS WITH DEEP NECK INFECTIONS AT CHO RAY HOSPITAL

Văn Công Ngô 1,, Minh Thịnh Trương 2
1 Cho Ray hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

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Abstract

Background: The LRINEC score was developed to early distinguish necrotizing fasciitis from other soft tissue infections. In addition, the LRINEC score can also predict poor outcomes. Objective: To investigate the association between the LRINEC score and necrotizing fasciitis in patients with deep neck infections and the association between the LRINEC score and complications of deep neck infections. Methods: We did a retrospectively and prospectively descriptive study of 62 cases of deep neck infections treated at Cho Ray Hospital from December 2019 to July 2022, with LRINEC scores calculated at the time of hospital admission. Results: There was no statistically significant association between the LRINEC score of the necrotizing fasciitis group and the non-necrotizing fasciitis group (OR=1.21; 95% CI: 0.96–1.53; p=0.1). The prognostic value of the LRINEC score for the diagnosis of necrotizing fasciitis is poor (AUC = 0.6079; 95% CI: 0.47 - 0.75). LRINEC score was associated with complications of deep neck infections (OR=1.48; 95% CI:1.14 - 1.92, p=0.003). The prognostic value of the LRINEC score for complications of deep neck infection is fair (AUC=0.7249; 95% CI: 0.59 - 0.86), with cut-off LRINEC score  ≥7 having a sensitivity of 77.1% and specificity of 74.1%. Conclusion: The LRINEC score is a useful tool in predicting complications of deep neck infections.

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References

1. Oguz H, Yilmaz MS. Diagnosis and management of necrotizing fasciitis of the head and neck. Curr Infect Dis Rep. Apr 2012;14(2):161-5. doi:10.1007/s11908-012-0240-1
2. Wong CH, Khin LW, Heng KS, Tan KC, Low CO. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Crit Care Med. Jul 2004; 32(7):1535-41. doi:10.1097/ 01.ccm.0000129486.35458.7d
3. El-Menyar A, Asim M, Mudali IN, Mekkodathil A, Latifi R, Al-Thani H. The laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring: the diagnostic and potential prognostic role. Scand J Trauma Resusc Emerg Med. Mar 7 2017;25(1):28. doi:10.1186/s13049-017-0359-z
4. Sandner A, Moritz S, Unverzagt S, Plontke SK, Metz D. Cervical Necrotizing Fasciitis--The Value of the Laboratory Risk Indicator for Necrotizing Fasciitis Score as an Indicative Parameter. J Oral Maxillofac Surg. Dec 2015;73 (12):2319-33. doi:10.1016/j.joms.2015.05.035
5. Sideris G, Sapountzi M, Malamas V, Papadimitriou N, Maragkoudakis P, Delides A. Early detecting cervical necrotizing fasciitis from deep neck infections: a study of 550 patients. Eur Arch Otorhinolaryngol. Feb 9 2021;doi:10.1007/s00405-021-06653-4
6. Thomas AJ, Meyer TK. Retrospective evaluation of laboratory-based diagnostic tools for cervical necrotizing fasciitis. Laryngoscope. Dec 2012;122(12):2683-7. doi:10.1002/lary.23680
7. Hsiao CT, Chang CP, Huang TY, Chen YC, Fann WC. Prospective Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for Necrotizing Fasciitis of the Extremities. PLoS One. 2020;15(1):e0227748. doi:10.1371/journal.pone.0227748
8. Fiorella ML, Greco P, Madami LM, Giannico OV, Pontillo V, Quaranta N. New laboratory predictive tools in deep neck space infections. Acta Otorhinolaryngol Ital. Oct 2020;40(5):332-337. doi:10.14639/0392-100x-n0790