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Date Published: 27/06/2023
Abstract Views: 78
Views PDF: 73
DOI: https://doi.org/10.51298/vmj.v527i1B.5753
Issue
Vol. 527 No. 1B (2023)
Section
Các bài báo
How to Cite
Lê, N. L., & Bùi, C. (2023). ASSESSMENT OF COMPOSITIVE COVERING CAPACITY OF DECELLULARIZED PIG PERICARDIAL IN THE MAXILLARY DEFECT IN RABBITS. Vietnam Medical Journal, 527(1B). https://doi.org/10.51298/vmj.v527i1B.5753

ASSESSMENT OF COMPOSITIVE COVERING CAPACITY OF DECELLULARIZED PIG PERICARDIAL IN THE MAXILLARY DEFECT IN RABBITS

Nguyên Lâm Lê1,, Cúc Bùi2
1 Can Tho University of Medicine - Pharmacy
2 Asian Cosmetic Dentistry

Main Article Content

Abstract

Background: Decellularized pig pericardial tissue holds promise to perform better than immobilized and regenerated tissue, but cell degranulation has been shown to damage collagen structure and impair integrity. tissue mechanics. Objective: To evaluate the ability to cover bone defects of decellularized pig pericardial on rabbit jawbone. Materials and methods: Research object: Decellularized pig pericardial produced from pig pericardium at the Biomaterials Laboratory - University of Natural Sciences, Vietnam National University, Ho Chi Minh City Minh. - Commercial acellular pericardium: Decellularized pig pericardial XenoGide, NIBEC (Korea) has been licensed for use. Neobone Commercial Bones, Portugal. Experimental Rabbits: Healthy, Non-Purebred New Zealand Rabbits. Research location: Biomaterials Laboratory - University of Natural Sciences, Vietnam National University, Ho Chi Minh City. Research period: from July 2021 to August 2022.2. Study design: a double-blind experimental descriptive study. Result: - The results showed that after 3 months of transplantation: the bone healing process in the transplant group with decellularized pig pericardial was similar to that of commercial pericardium: the bone healed completely after 3 months. - No infiltration of fibrous tissue was detected in the bone marrow and very few inflammatory cells were present. Conclusion: The dPP Decellularized pig pericardial is a good support for the bone healing process in the maxillary defect in rabbits.

Article Details

Keywords

: Acellular pericardium, covering

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