SAFETY PROFILE OF AB INTERNO TRABECULOTOMY IN PRIMARY OPEN-ANGLE GLAUCOMA TREATMENT

Tấn Đỗ1,, Thị Vân Anh Bùi1, Thái Đạt Nguyễn1
1 VIETNAM NATIONAL INSTITUTE OF OPHTHALMOLOGY

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Abstract

Objective: To evaluate the safety profile of ab interno trabeculotomy in treating primary open-angle glaucoma (POAG) with previously failed filtering surgery. Subjects and methods: Prospective study on the results of ab interno trabeculotomy in 32 eyes (29 patients) diagnosed with POAG with previously failed filtering surgery at the Glaucoma Department, Vietnam National Eye Hospital from March 2022 to December 2022. In the studied eyes, IOP was not controlled with at least two hypotenisve drugs. Intraocular pressure, number of medications and complication rate were collected and analysed by the medical statistical algorithms. The safety profile was analysed basing on the result of visual acuity, intraocular pressure, number of hypotensive drugs and especially the complication rate, failure rate at 1 week, 1 month. Results: The intraocular pressure reduction was significant after surgery. The mean preoperative IOP was 31.69 ± 9.76 mmHg decreased to 18.69 ± 5.57 mmHg with an average reduction of 37.12% ± 23.19% after 1 month. The visual acuity was preserved after 1 month. Ab interno trabeculotomy reduced drug dependence of the study group of patients. The mean preoperative number of medication was 3.09 ± 0.89 reduced to 1.06 ± 1.34 after 1 month. Ab interno trabeculotomy shown to be a minimally invasive glaucoma surgery technique, without vision-threatening complications which require second surgical intervention. Hyphema was the most common complication after surgery. Most of the hyphema cases were mild and nearly all resolved by the first postoperative month. Conclusion: The results showed a good safety profile of  ab interno trabeculotomy in treating primary open-angle glaucoma with previously failed filtering surgeries

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References

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