NGHIÊN CỨU SỰ BIẾN ĐỔI NỒNG ĐỘ NT-PROBNP HUYẾT TƯƠNG VÀ ĐẶC ĐIỂM RỐI LOẠN NHỊP TIM TIM Ở BỆNH NHÂN SUY TIM DO BỆNH TIM THIẾU MÁU CỤC BỘ MẠN TÍNH

Abstract

Objectives: To various plasma NT-proBNP and characteristics arrhythmia of the heart failure in stable ischemic heart disease. Subjects and methods: A cross-sectional descriptive study on 136 chronic heart failure were diagnosed as stable ischemic heart disease at Military Hospital 103 and Hanoi Heart Hospital from October 2016 to January 2021. Participants were eligible for inclusion and exclusion criteria. NT-proBNP was taken at the admission and after treatment. Medical statistical algorithm was used to determine the correlation between symptoms of heart failure, ventricular arrhythmia and plasma NT-proBNP. Results: The group  over 75 years old had the highest mean NT-proBNP level 3468,975 ± 7876,498 pg/ml. The group under 50 years old had the lowest value 519,139±160,953pg/ml. The difference was significant with p = 0.017. NT-proBNP all had changes, the older the group, the higher the value. NT-proBNP concentrations in the group with decreased left ventricular ejection function were found to be higher than those in the group with normal or slightly decreased left ventricular systolic function. The number of ventricular ectopic units also had a remarkable change before and after treatment, the number of ventricular extrasystole significantly decreased after the treatment, the difference was significant p <0.001. Conclusion: NT-proBNP are related to age and severity according to NYHA, and inverse association between NT-proBNP and left ventricular ejection function. Cardiac arrhythmias, especially premature ventricular complexes are most common in heart failure patients with chronic ischemic heart disease.