Article Sidebar

PDF
Date Published: 07/08/2023
Abstract Views: 305
Views PDF: 213
DOI: https://doi.org/10.51298/vmj.v528i2.6065
Issue
Vol. 528 No. 2 (2023)
Section
Các bài báo
How to Cite
Đoàn, L. V., Lê, M. S., Nguyễn, V. P., Nguyễn, T. L., Phạm, V. A. Q., Ngô, Đức Q., Nguyễn, V. Đạt, Vũ, Đình T., & Đỗ, T. H. (2023). INITIAL RESULT OF SURGERY TREATMENT FOR INFECTION AFTER FRACTURE FIXATION USING ANTIBIOTIC- LOADED POLYMETHYLMETHACRYLATE BEADS AND SPACER. Vietnam Medical Journal, 528(2). https://doi.org/10.51298/vmj.v528i2.6065

INITIAL RESULT OF SURGERY TREATMENT FOR INFECTION AFTER FRACTURE FIXATION USING ANTIBIOTIC- LOADED POLYMETHYLMETHACRYLATE BEADS AND SPACER

Lê Vinh Đoàn1,, Mạnh Sơn Lê1, Văn Phan Nguyễn1, Thành Luân Nguyễn1, Vũ Anh Quang Phạm1, Đức Quang Ngô1, Văn Đạt Nguyễn1, Đình Thắng Vũ1, Trọng Hùng Đỗ1
1 GERMANY FRIENDSHIP HOSPITAL

Main Article Content

Abstract

This study was conducted on 37 infected patients after surgery for internal fixation and external fixation who were treated at Viet Duc Hospital from 8/ 2021 to 8/2022 by using antibiotic-loaded polymethylmethacrylate beads and spacer. Objectives: Evalute the initial result of surgery treatment for infection after fracture fixation using antibiotic-loaded polymethylmethacrylate beads and spacer. Methods: This is a descriptive prospective study. We selected patients according to selection criteria, perform 2-stage surgery, re-examine and evaluate results after surgery 6 months. Results: At six- month posoperative, 1 patient (2.7%) had to re-operate due to recurrent infection, 36 patients (97.3%) had good scar healing, no fistula, no sign of recurrent infection. On X-ray, out of 36 patients, 33 patients (91.7%) have bone union, 2 patients (5.6%) have delayed union and 1 patient (2.7%) has non union, that was required a bone graft surgery. Conclusions: Surgery treatment for infection after fracture fixation using antibiotic- loaded polymethylmethacrylate is safe, effective, with few complications, high cure rate and high bone union rate.

Article Details

Keywords

infection after surgery, fracture fixation, spacer, beads, antibiotic-loaded polymethylmethacrylate

References

1. Kizkapan T.B., Misir A., Oguzkaya S. và cộng sự. (2021). Reliability of radiographic union scale in tibial fractures and modified radiographic union scale in tibial fractures scores in the evaluation of pediatric forearm fracture union. Jt Dis Relat Surg, 32(1), 185–191.
2. Nelson C.L. (2004). The current status of material used for depot delivery of drugs. Clin Orthop Relat Res, (427), 72–78.
3. Cierny G., Mader J (1983). The surgical treatment of adult osteomyelitis. New York, NY, USA: Churchill Livingstone, 4814–4834.
4. Willenegger H, Roth B (1986). Treatment tactics and late results in early infection following osteosynthesis. 12, 241–246.
5. Musahl V, Tarkin I, Kobbe P, et al (2009). New trends and techniques in open reduction and internal fixation of fractures of the tibial plateau. 9(14), 426–433.
6. Anagnostakos K. và Kelm J. (2009). Enhancement of antibiotic elution from acrylic bone cement. J Biomed Mater Res B Appl Biomater, 90(1), 467–475.
7. Kanakaris N., Gudipati S., Tosounidis T. và cộng sự. (2014). The treatment of intramedullary osteomyelitis of the femur and tibia using the Reamer-Irrigator-Aspirator system and antibiotic cement rods. Bone Joint J, 96-B(6), 783–788.
8. Morelli I, Drago L, George DA, Gallazzi E, Scarponi S, Romanò CL (2016). Masquelet technique: myth or reality? A systematic review and meta-analysis. 68–76.