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Date Published: 07/08/2023
Abstract Views: 239
Views PDF: 129
DOI: https://doi.org/10.51298/vmj.v528i2.6157
Issue
Vol. 528 No. 2 (2023)
Section
Các bài báo
How to Cite
Trần, T. H., Phạm, H. P., Hồ, T. P., Diệp, T. M. T., Trần, T. K. T., & Võ, D. T. (2023). RESEARCH OF CONTENTS AND CORRELATION BETWEEN SERUM CREATININE AND eGFR WITH SOME CLINICAL LABORATORIES IN PATIENTS WITH ACUTE PANCREATITIS AT CHO RAY HOSPITAL. Vietnam Medical Journal, 528(2). https://doi.org/10.51298/vmj.v528i2.6157

RESEARCH OF CONTENTS AND CORRELATION BETWEEN SERUM CREATININE AND eGFR WITH SOME CLINICAL LABORATORIES IN PATIENTS WITH ACUTE PANCREATITIS AT CHO RAY HOSPITAL

Thanh Hưng Trần1,, Hùng Phong Phạm1, Tấn Phát Hồ1, Thị Mộng Tuyền Diệp1, Thị Kim Thảo Trần1, Duy Thông Võ1,2
1 Cho Ray Hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objectives: To determine the concentration and correlation of serum creatinine and glomerular filtration rate at 24 hours and the first 48 hours with some laboratory tests in patients with acute pancreatitis. Methods: A descriptive cross-sectional study on 97 patients with acute pancreatitis diagnosed and treated at the Department of Gastroenterology and Special Care of Cho Ray Hospital from February 2015 to June 6. 2016. Results: The mean BUN concentration was 35.20 ± 30 mg/dL with the severe pancreatitis group and 12.88 ± 6.90 mg/dL with the mild pancreatitis group (p < 0.001). eGFR with Balthazar score (p < 0.05) and amylase were negatively correlated. The mean creatinine concentration in the severe pancreatitis group was 2.43 ± 1.82 mg/dL. In the mild pancreatitis group, it was 1.07 ± 0.20 mg/dL (p < 0.001). The eGFR concentration in the severe pancreatitis group was 40.45 ± 17.80 mL/min, and the average mild pancreatitis group was 58.78 ± 4.12 mL/min (p < 0.001). There was a relationship between creatinine levels, eGFR with the severity of acute pancreatitis; the recorded AUC of eGFR was 0.840 (with p < 0.001; CI: 0.746 - 0.934), creatinine with AUC of 0.855 (with p < 0.001; CI: 0.759 – 0.951); eGFR: cut-off point 54.41 mL/min with a sensitivity of 92%, a specificity of 75%; creatinine: cut-off point of 1.5 mg/dL with a sensitivity of 74.5%, specificity of 100%. Conclusion: Creatinine has a positive correlation, and glomerular filtration rate is negatively correlated with the severity of acute pancreatitis.

Article Details

Keywords

Acute pancreatitis, eGFR, Creatinine.

References

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