RISK FACTORS, DIAGNOSIS AND TREATMENT OF DELAYED GASTRIC EMPTYING POST SUBTOTAL GASTRECTOMY FOR GASTRIC CANCER

Nguyên Hưng Thái1,, Văn Linh Phan2
1 K hospital
2 HMU

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Abstract

Study aim: 1. Clinical and paraclinical feature and risk factors  of delayed gastric emptying post  subtotal gastrectomy for gastric cancer. 2. Diagnosis, treatment of delayed gastric emptying. Patient and method: +Retrospective study. +Case report  (rare diseases). Result: There were 4 patients; 2 male,2 female,mean age: 65,5 Y (Range: 60-72 Y), the average onset time post gastrectomy 10,75 day (range 10-12 day); of them, 3 patients had diabetes, one had emotional stress and anxiety preoperation. The lesion per operation:1 had pyloric obstruction,3 patient had tumors located at the body or lesser curvature of stomach. Operation performed: Subtotal gastrectomy with billroth 2 reconstruction (Finsterer) and lymph node D2 dissection. Clinical manifestations  post gastrectomy: nausea, bloating, vomiting Plain Xrays: No hydro -air level, no intertinal obstruction. Barium serial  Xrays (Telebrix): post 6 h: retained telebrix in lumen of remnant anastomosis, the transit time more than 12h for emptying all telebrix, dilatation of remnant stomach, no mecanichal obstruction (Telebrix went downward to colon). All patients had medical treatment consisting of nutrient support and erythromycin with half dosage orally. 3 of them had good recovery,one had acupuncture and electromechanics acupuncture. The average hospital stay (post onset delayed gastric emptying): 6,75 day (range 5-12 day). Conclusion: Delayed gastric emptying post subtotal gastrectomy appeared on 10,75 days (average time). Risk factors included:  Type 2 diabetes, pyloric obstruction, location of tumor in the lower body of stomach or lesser curvature. Diagnosis: Barium serial Xrays showed retained barium (telebrix) intra lumen of stomach remnant post 6 h with remnant anatomosis dilatation. Treatment consisted of: Nutrition support, naso tube aspiration, oral erythromycin (low dosage) in combination with electromechanics acupuncture.

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References

Trần Thanh Tùng: Nghiên cứu xạ hình làm trống dạ dày trong chẩn đoán liệt dạ dày ở bệnh nhân Parkingson.Luận án Tiến sỹ Y học.TP.HCM 2022.
2. Huang I-Hsuan et al: Prevalence of delayed gastric emptying in patients with gastroparesis like symptoms.Alimentary Pharmacology -Therapeutics.2023.Volume 57 (7):773-782
3. Linda E Watson et al: Gastric Emptying in Patients with Well-Controlled Type 2 Diabetes Compared With Young and Older control Subjects Without Diabetes.J Clin Endocrinol Metab,August 2019,104 (8):3311-3319.
4. Marcani L, SE Prichard, C Hellier-Wood, C Cortigan, CL Hoad, PA Gowland, RC Spiller: Delayed gastric emptying and reduced post prandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subject:Novel MRI insights
5. Meng. H, Dhou D, Jiang X,Ding W, Lul: Incidence and risk factors for post surgical gastroparesis syndrome after laparoscopic and open radical gastrectomy.World Journal Surg Oncol.2013;11:114
6. Oshima T et al: Genetic factors for functional dyspepsia. J.Gastroenterol Hepatol 2011; 26 (suppl 3): 83-7
7. Simren M: et al: Visceral Hypersensityvity is associated with GI symptom severity in functional GI disorders:conisisting findings from five difererent patient cohort.Gut.2018; 67:255-62.
8. Soenen S, Rayner CK, Horowitz M, Jones KL: Gastric emptying in the elderly.Clin Geriatr Med. 2015; 31:339-53.
9. Tao Pang, Xiao-YiYin, Hang-Tian Cui, Zheng-Mao Lu, Ming-Ming Nie, Kai Yin, Guo-En Fang, Tian-Hang luo and Xu-Chao Xue: Analysis of risk factors and prevention strategies for functional delayed gastric emptying in 1243 patients with distal gastric cancer. World journal of Surgical Oncology.2020,18:302.