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Date Published: 18/09/2023
Abstract Views: 192
Views pdf: 126
DOI: https://doi.org/10.51298/vmj.v530i1.6609
Issue
Vol. 530 No. 1 (2023)
Section
Các bài báo
How to Cite
Nguyễn, Đức P., Nguyễn, T. L., Trần, V. N., & Công, Q. T. (2023). TO COMPARE THE EFFECT OF SUGAMMADEX WITH NEOSTIGMINE IN REVERSAL OF ROCURONIUM MUSCLE RELAXANT AFTER ENDOSCOPIC THORACIC SURGERY. Vietnam Medical Journal, 530(1). https://doi.org/10.51298/vmj.v530i1.6609

TO COMPARE THE EFFECT OF SUGAMMADEX WITH NEOSTIGMINE IN REVERSAL OF ROCURONIUM MUSCLE RELAXANT AFTER ENDOSCOPIC THORACIC SURGERY

Đức Phương Nguyễn1,, Thành Long Nguyễn1, Văn Nam Trần1, Quyết Thắng Công2
1 Lung central hospital
2 HMU

Main Article Content

Abstract

Objective: To compare the effect of sugammadex with neostigmine in reversal of rocuronium muscle relaxant after endoscopic thoracic surgery. Subjects and methods: Using prospective study design, controlled clinical intervention. Group 1: 57 patients undergoing endoscopic thoracic surgery to reverse muscle relaxant with sugammadex 2mg/kg; Group 2: 57 patients undergoing endocscopic thoracic surgery to reverse muscle relaxant with a mixture of neostigmin 0.05mg/kg – atropine 0.01mg/ kg. Results: Time from muscle relaxant reversal injection to reaching TOF ≥ 0.7 and TOF ≥ 0.9 in group I was faster than the figure of group II, the difference was statistically significant with p<0,05. There was no statistically significant difference in the mean values of BIS between reversal of muscle relaxants and tracheal extubartion. Unwanted effects such as dry mouth, nausea, bradycardia were more common in the group of patients using neostigmine. Conclusion: Reversing agent of rocuronium after endoscopic thoracic surgery with sugammadex proved more effective than neostigmine.

Article Details

Keywords

rocuronium, sugammadex, neostigmin, endoscopic thoracic surgery

References

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