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Issue: Vol. 530 No. 1 (2023)
Section: Các bài báo
DOI: 10.51298/vmj.v530i1.6628
Date Published: 15/09/2023
Views 2458
Downloads 1005
How to Cite
Quế, A. T., & Ngô, T. P. O. (2023). RESEARCH CHARACTERISTICS OF ANTIBIOTIC RESISTANCE CHARACTERISTICS OF COMMON GRAM-NEGATIVE BACTERIA CAUSING SEPSIS AT NGHE AN GENERAL FRIENDSHIP HOSPITAL IN 2022. Vietnam Medical Journal, 530(1). https://doi.org/10.51298/vmj.v530i1.6628

RESEARCH CHARACTERISTICS OF ANTIBIOTIC RESISTANCE CHARACTERISTICS OF COMMON GRAM-NEGATIVE BACTERIA CAUSING SEPSIS AT NGHE AN GENERAL FRIENDSHIP HOSPITAL IN 2022

Anh Trâm Quế1, Thị Phương Oanh Ngô2,
1 NGHE AN FRIENDSHIP GENERAL HOSPITAL
2 HUPH

Main Article Content

Abstract

Background: Gram-negative bacteria are the common cause of sepsis and have increasing antibiotic resistance and multi-resistance tends to increase. Providing information on antibiotic resistance of Gram-negative bacteria is essential for clinical practice. Objective: To study antibiotic resistance characteristics of common gram-negative bacteria causing sepsis at Nghe An General Friendship Hospital. Subjects and methods: A cross-sectional descriptive study, 428 strains of Gram-negative bacteria causing sepsis were collected at Nghe An General Friendship Hospital from 1/2021 to 12/2021. Results: E. coli was resistant to all tested antibiotics: highest with Ampicillin 89.6%, lowest with Fosfomycin 3%, the rate of ESBL-producing is 54.5%. K. pneumoniae was resistant to all tested antibiotics: highest with Ampicillin/Sulbactam 57.1%, lowest with Fosfomycin 11.4%, the rate of ESBL-producing is 15.9%. Burkholderia pseudomallei has not recorded resistance to Carbapenem, Ceftazidime, and resistance to Cotrimoxazone 27.6%. Regarding the type of multi-antibiotic resistance, E. coli had the highest rate of multi-resistance at 80.6%, followed by K. pneumoniae 59.7%. K. pneumoniae has an expanded resistance rate of 23.6%, higher than E. coli (9.3%). MDR, XDR of Burkholderia pseudomallei have not been recorded. Conclusion: The E. coli strain in our study has a relatively high rate of antibiotic resistance and multi-resistance. The proportion of K. pneumoniae with extended resistance is higher than that of E. coli. Multiple resistance and extended multidrug resistance of Burkholderia pseudomallei have not been recorded

Keywords

Gram-negative bacteria, anti-blood, antibiotic, resistant, multi-resistant

Article Details

References

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