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Date Published: 18/09/2023
Abstract Views: 1114
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DOI: https://doi.org/10.51298/vmj.v530i1.6628
Issue
Vol. 530 No. 1 (2023)
Section
Các bài báo
How to Cite
Quế, A. T., & Ngô, T. P. O. (2023). RESEARCH CHARACTERISTICS OF ANTIBIOTIC RESISTANCE CHARACTERISTICS OF COMMON GRAM-NEGATIVE BACTERIA CAUSING SEPSIS AT NGHE AN GENERAL FRIENDSHIP HOSPITAL IN 2022. Vietnam Medical Journal, 530(1). https://doi.org/10.51298/vmj.v530i1.6628

RESEARCH CHARACTERISTICS OF ANTIBIOTIC RESISTANCE CHARACTERISTICS OF COMMON GRAM-NEGATIVE BACTERIA CAUSING SEPSIS AT NGHE AN GENERAL FRIENDSHIP HOSPITAL IN 2022

Anh Trâm Quế1, Thị Phương Oanh Ngô2,
1 NGHE AN FRIENDSHIP GENERAL HOSPITAL
2 HUPH

Main Article Content

Abstract

Background: Gram-negative bacteria are the common cause of sepsis and have increasing antibiotic resistance and multi-resistance tends to increase. Providing information on antibiotic resistance of Gram-negative bacteria is essential for clinical practice. Objective: To study antibiotic resistance characteristics of common gram-negative bacteria causing sepsis at Nghe An General Friendship Hospital. Subjects and methods: A cross-sectional descriptive study, 428 strains of Gram-negative bacteria causing sepsis were collected at Nghe An General Friendship Hospital from 1/2021 to 12/2021. Results: E. coli was resistant to all tested antibiotics: highest with Ampicillin 89.6%, lowest with Fosfomycin 3%, the rate of ESBL-producing is 54.5%. K. pneumoniae was resistant to all tested antibiotics: highest with Ampicillin/Sulbactam 57.1%, lowest with Fosfomycin 11.4%, the rate of ESBL-producing is 15.9%. Burkholderia pseudomallei has not recorded resistance to Carbapenem, Ceftazidime, and resistance to Cotrimoxazone 27.6%. Regarding the type of multi-antibiotic resistance, E. coli had the highest rate of multi-resistance at 80.6%, followed by K. pneumoniae 59.7%. K. pneumoniae has an expanded resistance rate of 23.6%, higher than E. coli (9.3%). MDR, XDR of Burkholderia pseudomallei have not been recorded. Conclusion: The E. coli strain in our study has a relatively high rate of antibiotic resistance and multi-resistance. The proportion of K. pneumoniae with extended resistance is higher than that of E. coli. Multiple resistance and extended multidrug resistance of Burkholderia pseudomallei have not been recorded

Article Details

Keywords

Gram-negative bacteria, anti-blood, antibiotic, resistant, multi-resistant

References

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