NGHIÊN CỨU TƯƠNG TÁC THUỐC CÓ Ý NGHĨA LÂM SÀNG TRONG ĐƠN THUỐC BẢO HIỂM Y TẾ ĐIỀU TRỊ NGOẠI TRÚ TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ NĂM 2022

Abstract

Objectives: Determine the rate and extent of clinically significant drug interactions in prescriptions, find out some factors that lead to the use of drugs that cause clinically significant interactions in medical insurance prescriptions for outpatient treatment at Can Tho University of Medicine and Pharmacy Hosoital. Materials and methods: A cross-sectional descriptive study with analysis based on 1700 outpatient medical insurance prescriptions at the Can Tho University of Medicine and Pharmacy Hospital from 01/07/2022 to 31/12/2022. Results: The rate of prescriptions with clinically significant drug interactions was 32.1%. The rate of clinically significant drug interactions with prescriptions of 2-4 drugs is 16.7%, prescriptions of 5-7 drugs are 52.1%, and prescriptions of 8 drugs or more are 89.2%. There is a relationship between clinically significant drug interactions with the patient's age, the number of comorbidities, the number of drugs in the prescription (p<0.001). Conclusions: The rate of clinically significant drug interactions occurring in outpatient health insurance prescriptions increases with increasing patient age, number of comorbidities and number of medications used. (p<0.001).