ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN XUẤT HUYẾT TIÊU HÓA CAO DO VIÊM LOÉT DẠ DÀY TÁ TRÀNG Ở BỆNH NHÂN DÙNG THUỐC CHỐNG NGƯNG TẬP TIỂU CẦU

Abstract

Objectives: To investigate clinical and laboratory characteristics of high gastrointestinal bleeding in patients using antiplatelet drugs. Methods: Cross-sectional description of 52 patients who used antiplatelet drugs at Bach Mai Hospital from August 2022 to May 2023. Patients with clinical manifestations of high suspicion of gastrointestinal bleeding were performed endoscopy for diagnosis and treatment. All patient information is collected in the research medical record. Results: The single and dual antiplatelet groups were similar in age and sex. The dual group had a higher history of gastrointestinal bleeding (88.9% versus 73.5%), blue skin, and pale mucous membranes in 100%, higher than the single group (76.5%), p<0, 05. There were no differences in other clinical symptoms and laboratory tests between the 2 groups. Regarding endoscopy, the dual group mainly had low risk (61.1%), without intervention (83.3%), and treated with blood transfusion (89.9%). The single group was mainly at high risk (55.9%), requiring intervention (38.2%) and treatment with blood transfusion (67.6%). There was no difference in Lanza, Rockall, Glasgow-Blatchford scores between the two groups. Conclusion: High gastrointestinal bleeding due to peptic ulcer disease has similarities in clinical, laboratory, and endoscopic features between the single and dual antiplatelet groups.