THE SIGNIFICANCE OF NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE (N-CPAP) VENTILATION IN TREATING SEVERE HEART FAILURE FOR CHILDREN HAVING CONGENITAL HEART DISEASE (CHD) WITH INCREASED PULMONARY BLOOD FLOW

Thị Linh Đoàn 1, Hồng Quang Lê2,, Ngọc Sáng Nguyễn 1, Thị Vân Anh Nguyễn 2, Thị Ngọc Anh Phạm 2, Thanh Huyền Ngô 2
1 Hai Phong University Of Medicine And Pharmacy
2 Vietnam National Children's Hospital.

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Abstract

Objective: The study aims to investigate the role of N-CPAP ventilation in treating severe heart failure for children having CHD with increased pulmonary blood flow. Methods: A one-group quasi-experimental study design was employed to examine the effectiveness of N-CPAP ventilation on the treatment of severe heart failure for a convenience sample of 42 eligible children from August 2021 to July 2022. All children (ages ranging from 2 months to 16 years of age) who had a diagnosis of  severe heart failure (class IV) caused by CHD with increased pulmonary blood flow received treatment-CPAP ventilation at Heart Center, the National Children's Hospital. Results: Among 42 children, ages ranged from 2 months to 16 years of age with the mean age at 5.49 months (SD = 4.6). The mean weight of these children (n=42) was 8.32 kg (SD = 5.67). Children with ventricular septal defect (n = 14) held the largest propotion with 33.2%. About 29 children (69%) had their heart failure successfully treated using N-CPAP ventilation in compared to a number of 13 children (31%) who did not recover from the administration of this treatment. The children who had successful treatment using N-CPAP ventilation had shorter mean hospital stay (M = 7.26, SD = 5.67) than those did not (M = 14.2, SD = 2.8). The percentage of children with severe heart failure after the administration of N-CPAP ventilation dramatically decreased from 100% to 21.4%. There were significant drops of heart rate (p<.01), respiratory rate (p<.01), oxygen saturation (p<.01) and pH (p<.001) in this population before and after the application of N-CPAP ventilation. Only seven children (16.7%) and about five children (11.9%) presented with mild complications of N-CPAP ventilation, including nasal pressure ulcer and abdominal distension,. Conclusions: The administration of N-CPAP ventilation may contribute to the improvement of clinical symptoms of severe heart failure among children having CHD with increased pulmonary blood flow.

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References

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