NGHIÊN CỨU ĐẶC ĐIỂM TUỔI, GIỚI VÀ MỐI LIÊN QUAN ĐẾN TỈ LỆ NHIỄM VIRUS DENGUE Ở BỆNH NHÂN NHI

Abstract

Objectives: Analyze age, gender characteristics, and association with dengue virus prevalence in pediatric patients. Subjects and methods: 344 pediatric patients diagnosed with febrile dengue phase within three days of fever, admitted to the Department of Pediatrics at Children Hospital No.1 in Ho Chi Minh City, Tien Giang General Hospital and Dong Nai Children Hospital from January 2011 to December 2015, Participation in the study was voluntary and agreed to participate in the study by their relatives and family members. Proceeding to collect information about the patient's age, gender, serum, and RNA extraction, using Multiplex RT-PCR reaction to determine the serotypes of Dengue virus. Results: Patients of all ages range infected with all four serotype viruses: type 1 (DENV-1), type 2 (DENV-2), type 3 (DENV-3), and type 4 (DENV-4). Of which, the age range 6-10 accounts for the highest percentage (50.43% - 63.24%), followed by the age range 11-15 (23.53% - 38.46%), and the lowest is about age ≤ 5 (11.11% - 15.79%) for all four virus serotypes, however, there is no age difference between the virus serotypes, with p = 0.1338. The rates of viral infections of the two sexes were similar for types 1, 2, and 4. In type 3, the girls (63.16%) was higher than in boys (36.84%), but the difference was not statistically significant with p = 0.2513. Conclusion: There is no difference in age and gender of viral serotype infections. However, at the age of 6-10, viral infection accounts for the highest rate in all four types, the incidence of type 3 infection in girls higher in boys.