EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTICS IN PATIENTS WITH MALIGNANT PLEURAL EFFUSION AT PHAM NGOC THACH HOSPITAL

Thành Đạt Lê1,, Đình Thắng Nguyễn 1, Thái Thụ Trần 1, Hồ Gia Phúc Lâm 1
1 Pham Ngoc Thach University of Medicine

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Abstract

Objective: Describe epidemiological and clinical characteristics in patients with malignant pleural effusion and comparing the differences between this group and the group without malignant pleural effusion at Pham Ngoc Thach Hospital. Subject  and  methods: A retrospective study was conducted on patients diagnosed with pleural effusion at Pham Ngoc Thach Hospital from 01/2017 to 07/2019. Results: The age of patients with malignant pleural effusion is 62.1 ± 13.1 years. The male-to-female ratio in the malignant pleural effusion group is 1.01. The average white blood cell count in malignant pleural effusion is 12.2 ± 4.4 K/μL, LDH 557,4 ± 369 U/L, protein 43,5 ± 8,9 G/L, creatinin 83,4 ± 18,3 μmol/L. Among patients with malignant pleural effusion, 50.5% have fluid accumulation on the right side, 49% have a large volume of fluid, and 53.2% have a yellowish lemon fluid color. The average protein level in the malignant pleural effusion group is 43.5 ± 8.9 g/L, the average LDH level is 865.5 ± 591.7 U/L, the average glucose level is 6.4 ± 4.2 mmol/L, and the average ADA level is 17 ± 49.7 U/L. Malignant pleural effusion cases have an average cell count of 1214.7 ± 1243.3 cells/mm3, with a predominance of lymphocytes. 40.2% of cases show lung tumors on chest CT scans. Conclusion: The age of patients with malignant pleural effusion is 62.1 ± 13.1 years, which is higher than the non-malignant pleural effusion group, and there is a difference in gender distribution between the two groups. There are several differences in clinical characteristics between patients with and without malignant pleural effusion.

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