GIÁ TRỊ CỦA SINH THIẾT TỨC THÌ VÙNG RÌA TRONG PHẪU THUẬT UNG THƯ HẠ HỌNG

Abstract

Background: Frozen section (FS) is a histopathological test that gives quick results in 10-20 minutes. FS is performed intraoperatively to help surgeons make decisions for the surgery as well as the next treatment plan. Objectives: To describe clinical and subclinical features of hypopharyngeal cancer with indications for surgery. Compare the results of FS with gross lesions to have experience in surgery. Objects and methods: The research method is a cross-sectional description. Objects include 54 patients diagnosed with hypopharyngeal cancer and operated on at the National Otolaryngology Hospital from 5/2022 to 6/2023 with preoperative biopsy results and intraoperative frozen section assessed the tumor margin area. Results: mean age 62.1 years. The most common tumor location is the pyriform sinus at 87.0%. Wart lesions 74.1%. The majority of patients come to the clinic in stages 3 and 4 with 40 cases (74.1%). Out of 209 samples for FS, there are 15 samples with positive results, accounting for 7.2%, of which the rate of FS samples in the margin region is positive in the group that has a margin region ≤ 1cm from the tumor is 11/209 samples (5.3%), the group that has a margin region at 1.2 - 1.5cm from the tumor was 4/209 (1.9%). Samples with a margin region > 1.5 cm from the tumor are all negative results. Conclusion: The most common tumor location is the pyriform sinus, and the most shape of the tumor is a wart. Histopathology is primarily a squamous cell carcinoma. Frozen section is an effective method, which plays a very important role in helping guide surgeons in surgery.