OUTCOMES OF SINONASAL INVERTED PAPILLOMA RESECTION BY ENDOSCOPIC SURGERY

Thị Hương Giang Nguyễn1,, Trần Anh Phạm1,2
1 HMU
2 Central Ear, Nose and Throat Hospital

Main Article Content

Abstract

Objectives: Characterization of studies on endoscopic surgery for the treatment of inverted nasopharyngeal papilloma and results of endoscopic surgery. Subjects and methods: Articles and studies in databases Pubmed, Google Scholar, library of Hanoi Medical University met the research criteria. Result: Found 758 documents. After analysis, 13 articles with a total of 804 patients were included in the study, of which 12 were on the group of patients with inverted nasopharyngeal papilloma, regardless of location, 1 study in the group of patients with inverted papilloma extending to the frontal sinus. Some characteristics of the studies: retrospective study design 84.6% (11), prospective study 15.4% (2) and sample size of studies under 50 people accounted for 61.5% (8). In 12 studies, the average age of participants was between 50 and 60 years old 66.8%. According to Krouse’s staging system: patients in T1 stage accounted for 15.8% (127), T2 stage accounted for 39.8% (320), T3 stage accounted for 42% (338), T4 stage accounted for 2.4% (19). Results of treatment with endoscopic surgery: the overall recurrence rate is 13.1%, this rate is very different between studies from 0 to 43.8%. 5/13 studies did not record complications due to endoscopic surgery, in the studies where complications occurred, the rate ranged from 2.1% to 7.7%, complications encountered in order gradually decreased: nosebleeds, swelling around the orbits, lacrimation, no serious complications such as cerebrospinal fluid leakage. Average recurrence time was from 7.5 months to 22 months with an average follow-up time from 19 months to 66 months, a minimum follow-up of 5 years (60 months) is recommened.

Article Details

References

1. Lawson W, Ho BT, Shaari CM and Biller HF: Inverted papilloma: a report of 112 cases. Laryngoscope 105: 228-288,1995.
2. Hyams VJ: Papillomas of the nasal cavity and paranasal sinuses: a clinicopathological study of 315 cases. Ann Otol Rhinol Laryngol 80: 192-206,1971.
3. Krouse JH. Development of a staging system for inverted papilloma. Laryngoscope. 2000; 110 (6): 965-968. doi: 10.1097/00005537-200006000-00015.
4. Goudakos JK, Blioskas S, Nikolaou A, Vlachtsis K, Karkos P, Markou KD. Endoscopic resection of sinonasal inverted papilloma: systematic review and meta-analysis. Am J Rhinol Allergy. 2018;32(3):167–74.
5. Busquets JM, Hwang PH. Endoscopic resection of sinonasal inverted papilloma: a meta-nalysis. Otolaryngol Head Neck Surg. 2006; 134(3): 476482.doi:10.1016/j.otohns.2005.11.038