Article Sidebar

PDF
Date Published: 07/12/2023
Abstract Views: 80
Views PDF: 50
DOI: https://doi.org/10.51298/vmj.v532i1B.7541
Issue
Vol. 532 No. 1B (2023)
Section
Các bài báo
How to Cite
Trần, T. K. U., Hoàng, T. T., Trần, M. A., & Lê, T. K. X. (2023). EVALUATING RETINAL NERVE FIBER LAYER CHANGES IN OPEN-ANGLE GLAUCOMA PATIENTS AT HA DONG EYE HOSPITAL. Vietnam Medical Journal, 532(1B). https://doi.org/10.51298/vmj.v532i1B.7541

EVALUATING RETINAL NERVE FIBER LAYER CHANGES IN OPEN-ANGLE GLAUCOMA PATIENTS AT HA DONG EYE HOSPITAL

Thị Kim Uyên Trần1,, Trần Thanh Hoàng1, Minh Anh Trần2, Thị Kim Xuân Lê3
1 Ha Dong Eye Hospital
2 HMU
3 Central Eye Hospital

Main Article Content

Abstract

Objective: To assess changes in the retinal nerve fiber layer (RNFL) in open-angle glaucoma patients at Ha Đong Eye Hospital. Research method: Descriptive cross-sectional study on 30 diagnosed open-angle glaucoma patients at Ha Đong Eye Hospital. Results: The study group included 48 eyes from 30 patients. The following results were obtained: Average age: 35.14 ± 16.51. Average intraocular pressure: 15.43 ± 5.16 mmHg. Average macular thickness: 542 ± 32.05 µm. Average equivalent spherical refractive error: > 5.674 ± 6.075D. Average optic disc diameter: 23.72 ± 1.86 mm. The average RNFL thickness and thinning in all quadrants were much greater than in severe primary open-angle glaucoma (POAG) and severe POAG: 64.16 ± 18.46. The degree of optic nerve damage was relatively severe with MD -17.49 ± 11.27 and PSD 5.09 ± 2.46. Conclusion: The study on 48 eyes has collected normal values of macular thickness, intraocular pressure, disc-to-cup ratio, optic disc diameter, RNFL thickness, and visual field. The results help identify changes in RNFL thickness closely related to refractive error and optic disc diameter. The rim area is related to the degree of myopia, optic disc diameter, and glaucoma stage. RNFL thickness varies more with glaucoma stage and degree of myopia

Article Details

Keywords

Glaucoma, retinal nerve fiber layer thickness, myopia, optical coherence tomography.

References

1. Schuman, J.S., Hee, M.R., Arya, A.V. et al. (1995), Optical coherence tomography: a new tool for glaucoma diagnosis. Curr Opin Ophthalmol, 6: 89-95
2. Hood, D.C. and Kardon, R.H. (2007), A framework for comparing structural and functional measures of glaucomatous damage. Prog Retin Eye Res. 26: 688-710
3. Park HY,Choi JA, Shin HY, Park CK. Optic disc characteristics in patients with glaucoma and combined superior and inferior retinal nerve fiber layer defects. JAMA Ophthalmol. 2014 Sep;132(9):1068-75.
4. Leung, C.K., Liu, S., Weinreb, R.N. et al. Evaluation of retinal nerve fiber layer progression in glaucoma a prospective analysis with neuroretinal rim and visual field progression. Ophthalmology. 2011; 118: 1551-1557
5. Xin, D., Greenstein, V.C., Ritch, R. et al. A comparison of functional and structural measures for identifying progression of glaucoma. Invest Ophthalmol Vis Sci. 2011; 52: 519-526
6. Bilgin S. The Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness in Adult Offspring of Primary Open-angle Glaucoma Patients. J Glaucoma. 2020;29(9):819-822.
7. Wang G, Medeiros FA, Barshop BA, Weinreb RN. Total plasma homocysteine and primary open-angle glaucoma. Am J Ophthalmol. 2004;137(3):401-406.
8. The AGIS Investigators. The advanced glaucoma intervention study (AGIS): 1. Study design and methods and baseline characteristics of study patients. Ophthalmology. 1993; 15: 299-325
9. Shin, J.W., Sung, K.R., Lee, G.C. et al. Ganglion cell-inner plexiform layer change detected by optical coherence tomography indicates progression in advanced glaucoma. Ophthalmology. 2017;124: 1466-1474.
10. Zhang, X., Dastiridou, A., Francis, B.A. et al. Comparison of glaucoma progression by optical coherence tomography and visual field. Am J Ophthalmol. 2017; 184: 63-74