TUÂN THỦ ĐIỀU TRỊ THUỐC CỦA NGƯỜI BỆNH PARKINSON ĐIỀU TRỊ NGOẠI TRÚ TẠI BỆNH VIỆN BẠCH MAI NĂM 2021 VÀ MỘT SỐ YẾU TỐ LIÊN QUAN

Abstract

Objectives: To describe the current medication adherence of Parkinson out-patients at Bach Mai Hospital in 2021 and to analyze some related factors. Methodology: A cross-sectional descriptive study with analysis was conducted on 160 Parkinson out- patients at the Neurology clinic of Bach Mai Hospital from 01/01 to 31/12/2021. Results: The rate of good medication adherence was 65%, the main reasons for non-adherence was forgetting to take medication (65%) and consuming additional functional foods (20%). The rates of medication reduction and treatment discontinuation were 20% and 33.1%, respectively. The primary reasons for poor medication adherence were: having multiple medications, reserving medication for future use, forgetting to carry medications while traveling, taking medications at incorrect times, missing doses, lack of reminders, fear of prolonged use leading to toxicity, and financial constraints. Statistically significant factors associated with adherence to pharmacotherapy included: having less than 3 types of medications (OR=2.4), being able to live independently (OR=3.1), having a mild to normal level of disease severity based on the MDS- Unified Parkinson's Disease Rating Scale- MDS-UPDRS (OR=3.4), and having health insurance coverage (OR=2.5). Gender, age and length of illness, frequency of medication use were not related significantly to patients’ medication adherence. Conclusions: The rate of good adherence to drug treatment (ADT) in Parkinson patients is not high, standing at 65%, with 65% of patients forgetting to take their medications, 33.1% discontinuing treatment, 20% reducing medication intake, and 20% consuming additional functional foods. The number of medications taken, the ability to live independently, disease severity based on the MDS-UPDR scale, and having health insurance coverage are statistically significant factors associated with medication adherence. It is essential to enhance guidance and counseling for patients and implement interventions to improve adherence, such as medication reminders, social support, and health insurance assistance.