GIÁ TRỊ THANG ĐIỂM MELD-ALBUMIN TRONG TIÊN LƯỢNG BỆNH NHÂN XƠ GAN

Abstract

Cirrhosis is a common chronic disease with a high mortality rate, so early prognosis is necessary. There are many prognostic scores, in which the MELD-Albumin score developed based on the MELD score and the serum Albumin have certain significance in the prognosis of cirrhosis patients within 3 months (90 days). Objective: To survey the MELD-Albumin score in cirrhosis patients. Comparing the MELD-Albumin score with MELD and MELDNa in predicting mortality in cirrhosis patients. Subjects and methods: Prospective descriptive method on 157 cirrhosis patients at Bach Mai Hospital. Results: The average age of study patients was 52.75±8.9 years. The disease is more common in men, accounting for 95.5%. The most common cause is alcohol at 68.8%, followed by hepatitis B virus 26.1%, hepatitis C virus 7% (1.9% of patients are co-infected with both hepatitis B virus and hepatitis C virus). The average MELD-Albumin score was 20.72±6.99. The MELD-Albumin score has prognostic value in cirrhosis patients after 30 days with AUROC 0.919 (p=0.000<0.05) and after 90 days with AUROC 0.896 (p=0.000<0.05). The area under the curve of the MELD-Albumin, MELDNa and MELD score predicting 90 days mortality is 0.896, 0.906, 0.882, with the cut-off point of the two MELD-Albumin and MELD score being 23, MELDNa is 22, which has a predictive value for mortality with statistical significance at p<0.05. Conclusion: MELD-Albumin score has significance in predicting 90 days mortality in cirrhosis patients.