ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ K¬¬ẾT QUẢ LỌC MÁU HẤP PHỤ TRÊN BỆNH NHÂN COVID-19 ĐIỀU TRỊ TẠI TỈNH NGHỆ AN

Abstract

Background: The treatment of COVID-19 patients, especially severe and critical patients, is still a challenge for the limited healthcare system in Vietnam. Hemodialysis adsorption has been shown to be an effective and safe method of removing cytokines in the treatment of COVID-19 patients. Objectives: 1). To describe the clinical and laboratory characteristics of COVID-19 patients undergoing adsorbent hemodialysis; 2). To comment on the treatment results of COVID-19 patients above. Research subjects and methods: A cross-sectional descriptive study on 28 COVID-19 patients receiving adsorbent hemodialysis treatment from 6/2021 to 12/2022 at the hospital where is treatment COVID 19 in Nghe An province. Results: The mean age of the study group was 61.7 ± 11.4 years. The youngest is 31 years old and the oldest is 87 years old. The male proportion is more dominant (53.6%) than women (46.4%). 92.8% of patients had dyspnea; fever accounted for 85.7%; dry cough accounted for 85.7%; loss of sense of smell accounted for 14.3%. The average blood pressure was 82.7±9.2mmHg; Pulse was 99.5± 13.4 l/min, SpO2 was 91.6±8.7%. Laboratory results: pH 7.33 ± 0.1; PaO2 77.4±34.2mmHg; PaO2/FiO2 123.6±91.1; CRP 110.4 ±94.7mg/l; ferritin 1791.4 ±1467.8ng/mL; LDH 418.8±142.4U/L; D-dimer 3646.2 ±4461.3 mcg/l.he average number of HA 330 dialyzers used was 3.1 ± 1.1 with the average HA 330 filtration time being 12.4 ± 4.7 hours and the anticoagulant used was mainly heparin (accounting for 96.4 %). Patients were underwent early adsorbent hemodialysis (before 72 hours) have a higher survival rate than patients with adsorbent hemodialysis after 72 hours. Conclusion: The most common symptoms in severe and critical COVID-19 patients were dyspnea, fever, and dry cough. The most common symptoms in severe and critical COVID-19 patients are difficulty breathing, fever, and dry cough. Patients were underwent early adsorbent hemodialysis (before 72 hours) have a higher survival rate than patients with adsorbent hemodialysis after 72 hours.