ĐÁNH GIÁ GIÁ TRỊ TIÊN LƯỢNG TỬ VONG CỦA SỐ LƯỢNG TIỂU CẦU Ở BỆNH NHÂN SỐC NHIỄM KHUẨN

Abstract

Objectives: Evaluate the change and mortality prognostic value of platelet count in the first 7 days in septic shock patients. Materials and method: Prospective Descriptive Study on 110 septic shock patients treated in the Center of Emergency, Intensive Care Medicine and Clinical Toxicology - 103 Military Hospital - Vietnam Military Medical University. Results: A total of 77.3% of septic shock patients had thrombocytopenia. In the survival group, the platelet count gradually decreased in the first 3 days, reaching the lowest value on the 3^rd day, then increased on the 5^th and 7^th day, while in the death group, the platelet count gradually decreased over study time points and reached the lowest value on 7^th day. The platelet count in the death group was significantly lower than the survival group, p<0.01. The thrombocytopenia group had a higher risk of death than the group without thrombocytopenia, with OR=3.43 (95% CI: 1.35-8.72, p<0.01). The platelet count on the 3^rd, 5^th, and 7^th has a weak, quite good and quite good prognostic value for mortality with an AUC of 0.669; 0.703 and 0.795, p<0.01. Conclusions: The platelet count in the death group was significantly lower than that in the survival group. Thrombocytopenia is a valuable predicting mortality factor in septic shock patients. The platelet count has weak, quite good and quite good prognostic values for death on the 3^rd, 5^th and 7^th day in septic shock patients.