ĐẶC ĐIỂM NỒNG ĐỘ ALBUMIN HUYẾT THANH TẠI THỜI ĐIỂM NHẬP VIỆN TRÊN BỆNH NHÂN SỐC NHIỄM KHUẨN

Abstract

Objectives: Albumin is a protein in serum that has important roles in the physiological activities. Serum albumin concentration was depending on clinical situation, including septic shock with many systems complex changes. This study aims to characterize albumin concentrations in patients with septic shock at the time of admission. Methods: A cross-sectional description study, data was collected on  200 patients diagnosed with septic shock and treated at the Intensive Care Center of Bach Mai Hospital during the period from August 2022 to July 2023. Results: A 200-patients study with the ratio male/female: 2:1, mean age: 58.27 ± 18.42, the common classfication of age is 60-80 years old. The most common cause of septic shock was respiratory infection (51%). The mean albumin concentration: 26.3±5.85g/l (11.3- 45.6 g/l), in that the ratio albumin concentration below 25 g/l was 40%, there was no diffirences about albumin concentration in male and female patients (25.92 and 26.67, p > 0.05), at each BMI levels (25.52; 25.84; 28.03; 28.12 and 29 with p > 0.05). SOFA score and APACHE II indexes were higher in the group had albumin level below 25 g/l (12.14 with 11.11, 19.24 with 17.56, p < 0.05). Conclusion: Albumin concentration was lower in septic sock patients. Some factors as sex, age classfication, BMI levels and cause of infection did not make a difference about albumin levels. SOFA score and APACHE II score were higher in the group has albumin concentration lower than 25 g/l.