BIOLOGICAL CHARACTERISTICS OF THE DERMATOPYTES THAT CAUSE ONYCHOMYCOSIS

Hồng Mạnh Hoàng , Cẩm Vân Trần , Thị Hà Vinh Nguyễn

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Abstract

Objectives: To investigate biological and chemical features of dermatophytes that cause onychomycosis. Population and methods: Cross-sectional description on 149 patients diagnosed with onychomycosis at the National Hospital of Dermatology and Venereology from September 2022 to August 2023.The samples cultured on Sabouraud and cornmeal medium, observed gross and microscopic morphology and physical and chemical experiment. Results: 39 Of the 149 culture samples were positive for dermatophytes;Average colonization time is 11.1± 2.7, the shortest time is 5 days for colonies of M.canis and the longest is 17 days for colonies of T.tonsurans; morphological characteristics of colonies on SDA medium are very diverse.The morphology of large spores and small spores of each strain is different. Biological and chemical tests show diversity and contribute to the identification of pathogenic fungal strains. Conclusion: Onychomycosis is a prevalent disease in our country with the main cause being dermatophytes. Culturing and examining the biological characteristics of fungal strains contributes to species biodiversity and determines the relationship between pathogenic strains and clinical characteristics.

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References

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