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CLINICAL AND SUBCLINICAL CHARACTERISTICS AND TREATMENT RESULTS OF TUBERCULOSIS MENINGITIS AT PHAM NGOC THACH HOSPITAL
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Abstract
Objective: Describe some clinical and subclinical characteristics and treatment results of tuberculous meningitis at Pham Ngoc Thach Hospital. Subject and methods: Retrospective study of medical records. Results: Common clinical symptoms at the time of admission: headache (87.2%), fever (55.1%), stiff neck (59%). Blood sodium concentration was 129.7 (111 – 142) mmol/L. The rate of tuberculosis abnormalities on plain chest X-rays is 50%. The number of patients with cerebrospinal fluid protein greater than 1 G/L is 46 patients, accounting for 59%, the number of patients with CSF glucose/blood glucose ratio < 0.5 in 66 patients (84.6%), the number of patients with CSF glucose/blood glucose ratio < 0.5 in 66 patients (84.6%). Cerebrospinal fluid cells were 100 - 500/mm3 in 34 patients, accounting for 43.6%, and 75 patients (96.2%) had a predominance of lymphocytes. The rate of treated patients with improved results at the time of discharge was 79.5%. Conclusion: Clinical symptoms are not specific, so other tests should be combined for a better diagnosis of tuberculosis meningitis.
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Keywords
Tuberculosis Meningitis, clinical characteristics, subclinical characteristics.
References
2. Seddon JA, Tugume L, Solomons R, et al, (2019), “The current global situation for tuberculous meningitis: epidemiology, diagnostics, treatment and outcomes”, Wellcome Open Res, 4(167), pp 167.
3. Dian S, Hermawan R, van Laarhoven A, et al, (2020), “Brain MRI findings in relation to clinical characteristics and outcome of tuberculous meningitis”, PLoS One, 15(11).
4. Kanesen D, Kandasamy R, Wong ASH, et al, (2021), “Clinical Outcome of Tuberculous Meningitis with Hydrocephalus - A Retrospective Study”, Malays J Med Sci, 28(5), pp 82-93.
5. Pehlivanoglu F, Yasar KK, Sengoz G, (2012), “Tuberculous meningitis in adults: a review of 160 cases”, ScientificWorldJournal, 2012, pp 169028.
6. S. Hosoglu MFG, I. Balik, B. Aygen, S. Erol, et al, (2002), “Loeb Predictors of outcome in patients with tuberculous meningitis”, Int J Tuberc Lung Dis, 6(1), pp 64 - 70.
7. Li X, Ma L, Zhang L, et al, (2019), “Clinical characteristics of tuberculous meningitis combined with cranial nerve palsy”, Clin Neurol Neurosurg, 184, pp 105443.
8. Youssef FG, Afifi SA, Azab AM, et al, (2006), “Differentiation of tuberculous meningitis from acute bacterial meningitis using simple clinical and laboratory parameters”, Diagn Microbiol Infect Dis, 55(4), pp 275-278.