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Date Published: 05/05/2024
Abstract Views: 76
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DOI: https://doi.org/10.51298/vmj.v538i1.9370
Issue
Vol. 538 No. 1 (2024)
Section
Các bài báo
How to Cite
Trần, T. H., Trần, C. L., & Phạm, T. V. A. (2024). STUDY ON THE ANALGESIC EFFECT OF “TD.NQ” CAPSULES ON EXPERIMENTAL ANIMAL. Vietnam Medical Journal, 538(1). https://doi.org/10.51298/vmj.v538i1.9370

STUDY ON THE ANALGESIC EFFECT OF “TD.NQ” CAPSULES ON EXPERIMENTAL ANIMAL

Thái Hà Trần, Công Luận Trần, Thị Vân Anh Phạm

Main Article Content

Abstract

Objective: Study the analgesic effect of "TD.NQ" capsules on a mouse model of knee osteoarthritis. Subjects and methods: Wistar white rats (provided by the Vietnam Military Medical Academy). Both breeds, healthy, weight 180 ± 40 g. Methods: study the analgesic effect of TD.NQ capsules on rats with MIA-induced knee osteoarthritis, using P.A.M pressure model and gauge pain threshold method. Results: TD.NQ dose of 4,266 g/kg has a clear analgesic effect on the P.A.M pressure model, an unclear analgesic effect on the gauge pain threshold method. TD.NQ dose of 12,798 g/kg has an analgesic effect on the P.A.M pressure model, the analgesic effect is unknown on the gauge pain threshold method. Conclusion: TD.NQ capsules with both doses of 4,266 g/kg and 12,798 g/kg have a clear pain-relieving effect on the P.A.M pressure model, but the effect is unclear on the gauge pain threshold method. The dose of 12,798 g/kg tends to have better effects but there is no statistically significant difference.

Article Details

Keywords

analgesia, TD.NQ, traditional medicine.

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