NGHIÊN CỨU ĐẶC ĐIỂM MỘT SỐ TỔN THƯƠNG CƠ QUAN ĐÍCH Ở BỆNH NHÂN TĂNG HUYẾT ÁP KHÓ KIỂM SOÁT TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ VÀ BỆNH VIỆN ĐA KHOA TRUNG ƯƠNG CẦN THƠ

Abstract

Background: In addition to being a major cardiovascular risk factor contributing to the global burden of disease and mortality, resistant hypertension is one of the diseases that presents several challenges in the treatment process. Target organ damage resulting from hyperemia will occur if uncontrolled extended high blood pressure is maintained. Changes in the anatomy and physiology of significant arteries and organs are typical signs of injury. The goal is to pinpoint specific organ damage and associated variables in resistant hypertensive patients. Objectives: Determine the extent of target organ damage and associated variables in individuals suffering from resistant hypertension. Materials and methods: patients were diagnosed with resistant hypertension at the Department of Interventional Cardiology – Neurology, Can Tho University of Medicine and Pharmacy Hospital and Can Tho Central General Hospital. Results: The most common causes of target organ damage are left ventricular concentric hypertrophy (65.3%) and proteinuria (75%). A logistic regression model study revealed that systolic blood pressure and eGFR levels were independently linked with target organ damage. The area under the curve (AUC) for predicting target organ damage is 0.995, with a p-value of 0.004. Conclusion: Assessing organ damage and regulating systolic blood pressure are crucial for individuals with difficult-to-control hypertension.