MỘT SỐ YẾU TỐ DỰ ĐOÁN MỨC ĐỘ NẶNG CỦA BỆNH NHÂN VIÊM TỤY CẤP

Abstract

Background: Predicting the severity in patients with acute pancreatitis helps to detect complications early so that timely intervention measures can be taken to reduce mortality. Objectives: To analyze some predictors of severity according to 2012 Atlanta criteria of patients with acute pancreatitis. Subjects and research methods: A cross-sectional descriptive study of 108 AP patients hospitalized at A9 Emergency Center, Bach Mai Hospital from January 2022 to June 2023. Results: Among 108 patients, the median age was 46±12,9  years; The male/female ratio is 4.4/1. Some factors predict the severity of acute pancreatitis: acute alcoholic pancreatitis (OR 0.4; 95% CI 0.16-0.99; p<0.05), Prothrombin <80% (OR 5, 3; 95%CI 2.17-13.4; p<0.01), Creatinine ≥120 mcmol/l (OR 15; 95%CI 4.7-48.3; p<0.01); LDH ≥500 UI/l (OR 19.7; 95%CI 6.7-57.7; p<0.01; Total blood calcium <1.7 mmol/l (OR 16.2; 95%CI 5) ,6-47; p<0.01 and BE<-5 mmol/l (OR 10.3; 95%CI 3.8-28.2; p<0.01) in which LDH ≥500 UI/l ( OR 6.7; 95%CI 1.7-26.2; p<0.01) and Creatin ≥120 mcmol/l (OR 6.3; 95%CI 1.08-36.7; p<0, 01) is an independent predictor of severe acute pancreatitis Conclusion: Several factors predict the severity of acute pancreatitis including: acute alcoholic pancreatitis, Prothrombin, Creatinine; Total blood calcium and BE