VAI TRÒ CỦA IGE ĐẶC HIỆU DỊ NGUYÊN TRONG CHẨN ĐOÁN CĂN NGUYÊN MÀY ĐAY MẠN TÍNH

Abstract

Objectives: To determine the relationship between the allergen-specific IgE antibody test (sIgE) and certain clinical and laboratory characteristics of chronic urticaria, in order to assess the role of sIgE in the causative diagnosis of chronic urticaria.Materials and methods: Cross-sectional descriptive study of 265 patients aged 18 years and older diagnosed with chronic urticaria, who met the inclusion and exclusion criteria. Results: There was a statistically significant relationship between the proportion of sIgE-positive patients with at least one allergen and those diagnosed with chronic inducible urticaria. This relationship was observed in patients with a history of atopy, disease duration of less than 1 year, daily symptoms, moderate or severe itch, skin rash lasting for more than 3 hours, mild and moderate angioedema, and a total IgE test result ≥ 100 kU/l. No statistically significant relationship was found between the proportion of sIgE-positive patients with at least one allergen and those experiencing symptoms of angioedema, the number of lesions within 24 hours, and leukocyte count, CRPhs, erythrocyte sedimentation, ANA, and temptest. Conclusion: The allergen-specific IgE test proves useful in the causative diagnosis of chronic urticaria for patients with certain clinical characteristics, particularly those with a history of atopy and a total IgE test result ≥ 100 kU/l.