EVALUATING THE EFFECTIVENESS OF PRE EXPOSURE PROPHYLAXIS (PrEP) ON MEN WHO HAVE SEX WITH MEN IN CAN THO 2022-2023

Mạnh Vũ Ngô, Thị Thu Hương Phan, Anh Tuấn Nguyễn, Thị Nhàn Đỗ, Thị Thùy Linh Đoàn, Hữu Thắng Nguyễn, Thị Nguyệt Minh Đoàn, Thị Hương Giang Phạm

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Abstract

According to the World Health Organization (WHO), proper HIV pre-exposure prophylaxis (PrEP) will reduce the risk of HIV infection for groups at high risk of HIV infection. The study followed 484 men who have sex with men (MSM) who participated in HIV pre-exposure prophylaxis (PrEP) in Can Tho in 2022-2023. The results showed that the study had 346 MSM (71.49%) using daily PrEP (Daily-PrEP) and 138 MSM (28.51%) using event-driven PrEP (ED-PrEP). The proportion of subjects maintaining PrEP for ≥3 months, ≥6 months, ≥9 months and ≥12 months was respective 74.6%; 65.9%; 54.7% and 48.4%. The ED-PrEP group had a higher retention rate than the Daily-PrEP group. The main reasons why subjects stopped using PrEP were due to loss of follow-up, relocation, and no longer being at risk of HIV infection. The rate of subjects testing positive for HIV after 3 months of using PrEP was 0.56% (01 case used Daily-PrEP and 01 case used ED-PrEP), after 6 months of using PrEP was 0.63% ( both cases used ED-PrEP) and no subject tested positive for HIV after 9 and 12 months of maintaining PrEP treatment. During PrEP use, symptoms due to side effects of the drug appeared in the first 3 months: 1.7% of cases had nausea, 1.1% of subjects had dizziness and headaches; 0.3% of subjects had symptoms of flatulence. In the future, it is necessary to have specific strategies to overcome barriers such as fear of side effects, problems with transportation, housing, etc. to improve treatment acceptance and retention rates.

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References

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