PRE-DISCHARGE GUIDELINE-DIRECTED MEDICAL TREATMENT IN HEART FAILURE WITH REDUCED EJECTION FRACTION

Vũ Đạt Nguyễn, Văn Sĩ Nguyễn

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Abstract

Introduction: Heart failure is one of the leading causes of mortality and hospitalization in cardiovascular patients. The initiation of guideline-directed medical treatment (GDMT) is recommended early in the pre-discharge phase to facilitate optimal medication titration during outpatient management and potentially improve patient outcomes. Objective: To determine the rate of prescription of heart failure medications in patients having heart failure with reduced ejection fraction (HFrEF) during the pre-discharge phase. Method: A descriptive cross-sectional study was conducted on 110 heart failure patients with reduced ejection fraction discharged from cardiology department, Cho Ray Hospital. Medication prescriptions were recorded at the time of discharge. Adherence to heart failure treatment recommendations was independently assessed by a cardiologist based on the treatment guideline version 2022of the Vietnamese Ministry of Health. Results: The rates of pre-discharge prescription of heart failure medications associated with improved prognosis, including ACEi/ARB, ARNI, SGLT2 inhibitors, beta blockers and aldosterone antagonists, were 60.9%, 20.9%, 74.5%, 52.7%, and 79.1%, respectively. The rate of loop diuretic use was 48.2%. Conclusion: GDMT in patients with HFrEF during the pre-discharge phase needs to be optimized, particularly ARNI and beta-blocker therapy

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References

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