MỘT SỐ YẾU TỐ TIÊN LƯỢNG SỐC Ở TRẺ 12 THÁNG - 16 TUỔI MẮC SỐT XUẤT HUYẾT DENGUE CÓ DẤU HIỆU CẢNH BÁO TẠI CẦN THƠ: MỘT NGHIÊN CỨU CẮT NGANG, ĐƠN TRUNG TÂM

Abstract

Background: Dengue hemorrhagic fever shock in children is a severe form with a high risk of mortality. The demand for understanding predictive factors for shock is increasing to optimize early detection and management of this condition, especially in Dengue hemorrhagic fever with warning signs. Objectives: This study aims to identify some clinical and subclinical factors predicting shock in children with Dengue hemorrhagic fever with warning signs. Materials and methods: A cross-sectional descriptive study was conducted on children aged 12 months to 16 years diagnosed and treated for Dengue hemorrhagic fever with warning signs at Can Tho Children Hospital from April 2023 to January 2024. Results: A total of 104 subjects were selected (15 with shock and 89 without shock) and surveyed for clinical and subclinical characteristics. Logistic regression analysis shows that children exhibiting restlessness-lethargy were at a 4.51 times higher risk of shock (95%CI: 1.12-58.86; p = 0.041). Similarly, children with platelet count < 50,000/µL and hematocrit > 40% were found to have a higher risk of shock (OR = 1.56; 95%CI: 1.09-3.59; p = 0.046 and OR = 8.51; 95%CI: 1.87-103.65; p = 0.013, respectively). Abdominal effusion, in general, also increased the likelihood of shock by 12.40 times (95%CI: 1.2-127.74; p = 0.034). Conclusion: Altered severe consciousness, decreased platelet count, increased hematocrit, and abdominal effusion are significant prognostic factors for shock in children with Dengue hemorrhagic fever with warning signs. Early identification of these risk factors may help timely management and potentially reduce the shock-related mortality rate.