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Date Published: 13/09/2021
Abstract Views: 395
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DOI: https://doi.org/10.51298/vmj.v505i2.1079
Issue
Vol. 505 No. 2 (2021)
Section
Các bài báo
How to Cite
Văn Khiên, V. ., Vũ Nam, Đoàn ., Quang Duật, N. ., Hồng Khánh, P. ., & Thị Huyền Trang, T. . (2021). INITIAL STUDY ON CAGPAI, OIPA, DUPA OF HELICOBACTER PYLORI IN DUODENAL ULCER PATIENTS IN VIETNAM. Vietnam Medical Journal, 505(2). https://doi.org/10.51298/vmj.v505i2.1079

INITIAL STUDY ON CAGPAI, OIPA, DUPA OF HELICOBACTER PYLORI IN DUODENAL ULCER PATIENTS IN VIETNAM

Vũ Văn Khiên1,, Đoàn Vũ Nam2, Nguyễn Quang Duật2, Phạm Hồng Khánh2, Trần Thị Huyền Trang1
1 108 Military Central Hospital
2 Military Hospital 103, Vietnam Military Medical University

Main Article Content

Abstract

Introduction: Since 1994, WHO has classified H.pylori in group I causing gastric cancer. However, the pathogenicity of H. pylori is highly dependent on its virulence factor. Research topic on the rate of cagPAI, oipA, dupA in duodenal ulcer patients in Vietnam. Patients and mehods: 43 patients with duodenal ulcer were confirmed on endoscopy and histopathology. CagPAI, oipA, dupA were performed by PCR. Results: Common age (31-59 years old): 60.5%. Male/Female ratio: 1.5. Common symptoms of duodenal ulcer include: epigastric pain, belching and heartburn. Number of patients with 01 ulcer: 88.4%. The rate of positive cagPAI, oipA, dupA in duodenal ulcer patients were  62.8%, 9.3%, 65.1%, respectively. Number of patients with 2 combined genes (cagPAI + dupA) were 19/34 (55.9%). Conclusion: The oipA gene of H. pylori is a high risk factor for duodenal ulcer in Vietnam. Need to study on more quantity

Article Details

Keywords

Helicobacter pylori, duodenal ulcer, gastric cancer, chronic gastritis

References

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