ĐẶC ĐIỂM LÂM SÀNG VÀ CHẤT LƯỢNG CUỘC SỐNG CỦA BỆNH NHÂN PARKINSON THỂ CỨNG

Abstract

Objective: Describe clinical characteristics and quality of life (Quality of Life - QoL) in Akinetic-rigid (AR) subtype of Parkinson's disease. Subjects and Methods: Cross-sectional descriptive study on 60 patients with AR subtype of Parkinson disease at the National Geriatric Hospital from August 2020 to June 2021, diagnosed with Parkinson's disease according to the criteria of the UK Parkinson's Disease Society Brain Bank (UKPDSBB/United Kingdom Parkinson's Disease Society Brain Bank), Akinetic-rigid (AR) subtype according to the Parkinson's Disease Assessment Scale (UPDRS), assess the quality of life of patients according to the Parkinson's Quality of Life Scale PDQ-39. Results: The average age of the study subjects was 68.3±8, the ratio of men and women were 56,7% and 43,4%. The most common mortor onset symtom was bradykinesia (93,3%), the most comnon non-motor onset were shoulder pain (56,7%) and sleep disorders (43,3%). Research subjects in phase III accounted for the highest rate of 40%. Quality of life in AR subtype of Parkinson disease in Mobiliy and Activities of daily living (ADL) was most affected with the mean score according to PDQ-39 (46,0±30,0 và 49,4±30,5). In the study, the group of patients in moderate-severe stage (stage III, IV, V) or group with disease duration of more than 5 years or patients with over 60 years old all had worse quality of life compared with other groups. These differencesare statistically significant with p<0.05. Conclusion: The quality of life of AR patients with Parkinson's disease is greatly affected, so it’s necessary for comprehensive care and attention from the medical team and family.