GIÁ TRỊ CỦA XUNG KHUẾCH TÁN TRONG UNG THƯ TUYẾN TIỀN LIỆT: VÙNG NGOẠI VI VÀ VÙNG CHUYỂN TIẾP

Abstract

Objectives: Evaluation of the value of diffusion weighted imaging (DWI) in the diagnosis of prostate cancer in the peripheral zone and the transition zone. Methods and subject: We reviewed the data of 74 patients including 296 lesions, who underwent magnetic resonance imaging of the prostate and had histopathological results. Suspected lesions were graded by PIRADs for DWI, then, the correlation between the imaging features on DWI and the histopathology of the lesion have DWI grade ≥ III would be analyzed. Results: Among 74 patients with 296 lesions, 182 (61.5%) suspected lesions on DWI (42.8% in peripheral zone, 57.2% in transition zone). Regression analysis showed a remarkable association between high DWI grade and the adverse pathological prognosis expressed by Gleason grade (all with p< 0.05). The concordance rate between DWI grade and histopathology was 77%, NV was remarkably higher than CT (87.8% and 69.9% with p=0.006). This result proved that there is a correlation between the increase in DWI grade and the malignancy of the lesion. Conclusions: In detecting tumors, DWI is more accurate in the peripheral zone than in the transition zone. The higher the DWI grade, the higher the accuracy. Meanwhile, prostate cancer could be found in a small proportion of negative DWI cases.