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Date Published: 10/03/2021
Abstract Views: 490
Views PDF: 565
DOI: https://doi.org/10.51298/vmj.v498i1.129
Issue
Vol. 498 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Mai Thùy, N., Anh Tuấn, T., & Việt Hùng, Đậu. (2021). RISK FACTORS ASSOCIATED WITH MORTALITY RATE FOR SEVERE ADENOVIVUS PNEUMONIA IN PICU OF THE NATIONAL CHILDREN HOSPITAL. Vietnam Medical Journal, 498(1). https://doi.org/10.51298/vmj.v498i1.129

RISK FACTORS ASSOCIATED WITH MORTALITY RATE FOR SEVERE ADENOVIVUS PNEUMONIA IN PICU OF THE NATIONAL CHILDREN HOSPITAL

Nguyễn Thị Mai Thùy1, Tạ Anh Tuấn2,, Đậu Việt Hùng2
1 Trường Đại học Y Hà nội
2 Bệnh viện Nhi Trung ương

Main Article Content

Abstract

Aims: Adenoviruse is an important pathogen of severe pneumonia in children. The study aimed to assess risk factors and outcomes with severe Adenovirus pneumonia. Methods: This cross – sectional descriptive study was conducted at the Pediatric Intensive Care Unit of the National Children Hospital from 11/2016 to 06/2018. All patients with confirmed diagnosis of severe Adenovirus pneumonia were included in the study. The characteristics and outcomes of the patients were compared usingc2test. Logistic regression analysis was performed to identify risk factors. Results: 90 patients with Adenovirus severe pneumonia were studied, mortality rate was 33,3%. Septic shock (OR= 2,8; 95%CI: 1,89 – 4,04),malnutrition (OR= 3,41;95%CI: 1,29 - 9,02), hepatomegaly (OR= 8,64; 95% CI: 2,89 – 25,8),severe pneumonia (OR=1,7; 95%CI: 1,4 – 2,08),interstitial pneumonia (OR= 7,5; 95%CI: 2,77 – 20,33),neutropenia (OR= 4;95%CI: 1,2- 13,6), leucocytosis (OR= 4,6; 95%CI: 1,4 – 15,0), lymphopenia (OR= 5,8; 95%CI: 1,4– 24,3), Hb <100 g/l (OR= 8,7; 95%CI: 1,9 – 40,03), Albumin ≤ 35g/l (OR= 16,8; 95%CI: 2,1 – 131,9), P/F < 200 (OR= 11,3; 95%CI: 1,4 – 90,9), Lactat > 2,5 (OR= 3,4;95%CI: 1,26 – 9,2) are factors that increase the risk of death in patients with severe adenovirus pneumonia.After using logistic regression analysis show the independent factors that predict the risk of death arehepatomegaly (OR= 8,4; 95%CI: 1,66 – 43,4); neutropenia (OR= 11,9; 95% CI:1,2 – 120,7). Conclusion: Mortality rate is high for severe Adenovirus pneumonia in children. Hepatomegaly and leucopenia are factors that increase the risk of death in patients with severe Adenovirus-associated pneumonia

Article Details

Keywords

Adenovirus, children, pneumonia, risk factor

References

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